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Biomedical subjects

A Mauro

Publications and source records attributed to A Mauro.

At least 109 records · Page 6Linked to original sources

[Isolation of Listeria spp., Aeromonas spp., and Vibrio spp. from seafood products].

Forty-one strains of Listeria, Aeromonas and Vibrio have been isolated in 71 samples of seafood, both raw and ready to eat and frozen. L. monocytogenes, detected by PCR also, is found in the smoked salmon only. Aeromonas spp. and Vibrio spp. are isolated in the raw products (shrimps and shellfish). No relationship is found between the presence of such microrganisms and the common indicator bacteria. Finally, the health hazard related to strong contamination and the need to diversify the food safety assurance programmes, for the various products, are underlined.

Aeromonas↗

The position of the head in space: a kinematic analysis in patients with cervical dystonia treated with botulinum toxin.

Many instruments have been employed in recent years in order to quantify the posture and motion of the head in normal and pathological subjects. Evaluations of this type present many difficulties related to the influence of individual and external factors and to the accuracy of the system used. In patients with cervical dystonia (CD) the only rating scales currently used are semi-quantitative and subjective. More precise information on disease severity and response to the treatment is needed. Posture and motion of the head were evaluated by means of ELITE motion analyser (BTS, Milan, Italy) in 6 patients with the left laterocollis form of CD undergoing treatment with botulinum toxin (BTX). The method emerged as very useful for the quantification of the therapeutic response (which was more marked in motion than in posture). We found an inverse relationship between the degree of motion improvement and the restriction of motion before treatment.

Adult↗

Noun verb dissociation in Parkinson's disease.

A noun/verb dissociation with a relative verb deficit was found in patients affected by Parkinson's disease, even in relatively early stages, when mental deterioration is not severe. This finding is compatible with earlier observations, according to which verbs are dealt with in more anterior regions with respect to nouns. It also supports the speculation that the co-ordination and the manipulation of information associated with a verb world rely on the frontostriatal system.

Adult↗

Oncogenes and growth factors in gliomas.

The activation of cellular proto-oncogenes is related to the genesis and progression of neoplasias. Protein growth factors and their cellular receptors have been identified as products of some proto-oncogenes. The role of epidermal growth factor receptor (EGFr) in gliomas is presented. The expression of mRNA for platelet-derived growth factor (PDGF) and PDGF B-type receptor (PDGF-rec-B) in gliomas is analyzed. Gliomas express "in vivo" PDGF.B and PDGF-rec-B mRNAs. PDGF.B mRNA levels correlate with GFAP mRNA and does not correlate with the degree of malignancy. This is in agreement with the hypothesis of an autocrine growth stimulation in gliomas. However some findings seem to indicate that in these tumors the PDGF-rec-B is preferentially expressed by vascular elements. Thus, also a paracrine loop for endothelial cell growth stimulation may be suggested in malignant gliomas.

Brain Neoplasms↗

Preferential expression of the dbl proto-oncogene in some neuroectodermal tumors.

The dbl oncogene belongs to a unique class of human transforming genes. The dbl proto-oncogene is activated by substitution of the 5' portion of the gene with an unrelated human sequence. The proto-oncogene product is distributed between the soluble and membrane fractions of the cytoplasm and its function remains still unknown. In order to understand the biological role of dbl in human malignancies or during cell differentiation we have investigated the expression of the dbl oncogene in a wide number of human tumors of different embryological derivation. We found that dbl is preferentially expressed in a few neoplastic histiotypes of neuroectodermal origin. The transcript size of 5.3 Kb strongly suggests that the gene is not truncated in these tumors. These data, together with the information that the proto-oncogene has been found expressed in normal brain and adrenal medulla, indicate that dbl expression may be involved in cell differentiation of some tissues of neuroectodermic origin.

Gene Expression Regulation, Neoplastic↗

[Incidence of fecal contamination in the samples of gicens and vegetables usually eaten uncooked (author's transl)].

The presence of E. coli has been found in the 48% of the samples of gicens and vegetables usually caten uncooked. The high incidence of fecal contamination suggests the necessity to build sewage plants, to forbid the use of superficial waters for irrigation and sanitary education to avoid alimentary contamination and enteric germ transmission.

Escherichia coli↗

[Salmonellosis in Messina during 1975-1977: epidemiological considerations and prophylactic recommendations (author's transl)].

The AA. report the results of the bacteriological researches carried during the years 1975-1977 on 8226 cultures. They remark the high percentage of positivity registered for Salmonella, with superiority of S. wien (87.74%), and the onset of serotypes of group E1. At the conclusion of their study point out the nature endemic taken by the salmonellosis in Messina, and suggest the practice of prophylaxis for the control of the epidemiology.

Adolescent↗

[Detection of Salmonella in the sea-water of Messina].

The AA. mede a research of Salmonellae in the sea water of the city of Messina (Italy), choosing 14 points near the sewage discharges. They used qualitative methods (Moore type buffers, inoculation of 50 ml of water in tetrationate 2 times concentrated) and quantitative methods (fractions of 100 ml of water in 10 parts and further inoculation in 10 tubes containing 20 ml of normal tetrationate each). The research conducted in June-July and November-December 1978 gave 50% positivity in the summer period and 100% in the winter period. They discuss the methods used and underline the difference of the two periods.

Anti-Bacterial Agents↗

[5 years of bacteriological analysis. Results and observations].

The Authors examined the bacteriological analysis carried our during a period of five years (June 1971-June 1976), and pointed out the percentage of positivity and sensibility to antibiotics of the bacteria isolated. On a total of 8,263 analysis, 4,327 coprocultures and 2,076 urinocultures have been made, thus occupying the first places in frequency. 195 patogenous enterobacteria have been isolated from coprocultures, corresponding to a positivity of 4.50%. As for the urinocultures positivity reached 43.25%; the germs most frequently isolated were Escherichia coli and Proteus mirabilis. The Authors isolated in the same period 17 strains of Myc. tuberculosis from 115 samples of expectoration (14.7%) and 27 strains from 216 samples of urine (12.5%). By recommending antibiograms, the Authors suggest that the most effective antibiotics against enterobacteria responsable of infections of the urinary and gastrointestinal tract are nalidixic acid and furadantin, cloramfenicolo was ineffective against the isolated Salmonella strains. As for Gram-positive germs some results have been obtained with cefalotine, rifampicin, and cefazolin.

Anti-Bacterial Agents↗

Solitary neurinoma of the anterior cranial fossa. Case report.

A case of solitary neurinoma of the anterior cranial fossa, protruding into the ethmoidal region and into the right orbita, in a 44-year old woman is reported. The four cases previously described are reviewed and the possible origin of these tumors is discussed.

Adult↗