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Biomedical subjects

A Matsuki

Publications and source records attributed to A Matsuki.

At least 451 records · Page 25Linked to original sources
PubMed1980

beta-Endorphin in obstetric analgesia.

Rapid and prolonged analgesia was obtained in all of 14 obstetric patients who received synthetic human beta-endorphin intrathecally at the time of delivery. Normal uterine contractions were maintained and all women were fully conscious and highly cooperative in the delivery process. No depression of respiration rate, cardiovascular or central nervous system was observed in any of the patients. Conditions of the infants evaluated by Apgar scoring were excellent. beta-endorphin must be administered intrathecally because it does not cross the blood-brain barrier; for the same reason, beta-endorphin cannot enter the central nervous system of the fetus as do opiates or other drugs commonly used as anesthetics or analgesics at the time of delivery.

Adolescent↗
PubMed1980

Effect of anaesthesia and surgery on endocrine function in elderly patients.

The effect of halothane-nitrous oxide anaesthesia and abdominal surgery on endocrine function was investigated in 18 elderly patients whose ages ranged from 65 to 77 (mean 69 years). Cortisol levels in plasma increased significantly during anaesthesia and surgery, and the increases were slightly higher than those in young adults. Plasma aldosterone increased and insulin levels did not change during the procedures, and these levels were lower than in younger adults. The endocrine responses in elderly patients were similar in magnitude to those in young adults. Therefore it appears that no special hormonal treatment is necessary for elderly patients undergoing routine surgical procedures.

Age Factors↗