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Biomedical subjects

A Mathur

Publications and source records attributed to A Mathur.

At least 289 records · Page 16Linked to original sources
PubMed1977

Relation between zinc content in saliva and blood in healthy human adults.

Measurements were made of zinc levels in saliva, whole blood and plasma as well as copper levels in plasma by atomic absorption spectrophotometry. The mean zinc concentration (in ppm) was 0.478 (n = 136) in resting mixed saliva, 0.046 (n = 36) in parotid saliva, 6.41 (n = 145) in whole blood and 0.87 (n = 145) in plasma. The whole blood zinc levels were significantly lower in females than in males (P less than 0.001). Females and blood donors (males) had a significantly (P less than 0.001) higher Cu:Zn ratio than males (non-donors). It would thus appear, first, that the local effect of salivary zinc cannot be assessed simply from the concentration of zinc in stimulated parotid saliva since about nine-tenths of the zinc in resting mixed saliva is derived from other sources and, second, that the Cu:Zn in plasma is the most eligible variable for detecting sub-clinical Zn deficiency.

Adult↗
PubMed1976

Role of rubella in congenital malformations in India.

In the present study rubella HI antibodies were determined in cases of congenital malformation and bad obstetric history to determine the role of rubella in such cases in India, as it has been reported to be rare in Japan in contrast to Western countries. The incidence of antibodies was statistically significant in cases of congenital eye, C.N.S., visceral and miscellaneous malformations and cases of spontaneous abortion and still-birth compared with controls of matching age groups. This is further supported by the demonstration of IgM antibodies in seven cases of congenital malformations and ten cases of spontaneous abortion. Our findings show that congenital rubella is not rare in India.

Abortion, Spontaneous↗
PubMed1976

Cardiac innnervation in the prenatal stages of Anas poecilorhyncha.

Innervation of the heart has been observed in the progressive developmental stages of Anas poecilorhyncha ranging from 8 h to 14 days stages using silver impregnation technique of Ungewitter (1951). Vagal cardiac fibres reach the atrial wall on the fourth day. Migration of nerve cells and ganglia has been observed from the more anterior regions to the heart along the precaval veins. The adult pattern of the heart is first established at the 8 days stage while the traces of the endocardial cushions are still present. The atrioventricular valves show rich innervation. The subepicardial ganglia and simple myocardial plexuses appear in the 8 days stage and become well differentiated on the 10th day. The subendocardial plexuses are reported to be sensory for the testing of the properties of the blood while the myocardial plexuses seem to have motor control over the working muscles of the heart specially those of the atria where rich innervation is observed. Local reflex areas have been described.

Animals↗
PubMed1975

An epidemic of picornavirus and adenovirus conjunctivitis.

A pandemic of acute haemorrhagic conjunctivitis occurred in south-east Asia during 1970 and 1971, and became epidemic in Lucknow in May 1971. From the conjunctival swabs adenovirus-like agents were isolated in monkey kidney tissue culture; one was typed as adenovirus 2. In paired sera rising antibody titres were found against an adeno-like agent isolated and the picornavirus (EC2/71) isolated in Singapore. The epidemics in south-east Asia were caused by a picornavirus while in Lucknow both adenovirus and picornavirus appeared to be implicated.

Acute Disease↗
PubMed1973

In vitro antiviral activity and preliminary clinical trials of a new adamantane compound.

A compound, 1'-methyl spiro (adamantane-2,3'-pyrrolidine) maleate, chemically related to the antiviral drug amantadine, was tested for activity in vitro against a number of human respiratory viruses. By a variety of techniques, it was shown to be active against a wide range of human and animal influenza A viruses. The effect was, however, variable and ranged from high activity against two 1957 Asian strains to no observable activity against a 1971 strain. Like amantadine, the drug did not inhibit the growth of influenza B viruses. It was also inactive against a number of paramyxoviruses. Unlike amantadine, the drug did inhibit rhinoviruses, but to a lesser extent than myxoviruses. The coronavirus 229E was also sensitive to the action of the drug in vitro. Although an earlier trial in volunteers showed that, when given orally from 2 days before until 5 days after virus challenge, the drug was protective against infection with influenza A/Hong Kong/68 virus, a similar trial in volunteers challenged with rhinoviruses 2 and 9 revealed no useful activity against rhinoviruses in man.

Animals↗