Search PubMed⌕ Search

Biomedical subjects

A Manunta

Publications and source records attributed to A Manunta.

50 records · Page 3Linked to original sources
PubMed1989

[Acute colonic hemorrhage. Importance of a preoperative localization of the origin of bleeding in patients requiring emergency surgery].

Conservative management of distal gastro-intestinal bleeding is successful in most cases; 10% of patients hospitalised with this diagnosis will however undergo emergency surgery. Preoperative localisation of the bleeding site allows to perform a limited, segmental colectomy even in emergency. This has been shown to be associated with a lower operative mortality and morbidity when compared with subtotal colectomy. In this retrospective study we reviewed the notes of 134 patients admitted with lower gastro-intestinal bleeding. 22 of these required more than 4 units of blood transfusion and 12 underwent emergency surgery. Preoperative localisation of the source of bleeding was possible in 7 cases (58%); the remaining 5 underwent a subtotal colectomy. The operative mortality was 8%. The Authors emphasise the importance of an aggressive diagnostic work up in all cases of massive bleeding (i.e. more than 4 units of blood requirement in the first 24 hours following hospitalisation) in order to minimise the number of emergency subtotal colectomy.

Acute Disease↗
PubMed1989

[Parotidectomy as prophylaxis in malignant melanoma of the fronto-temporal and eyelid skin].

Three patients presented with parotid masses which revealed, on frozen section, to be metastatic lesions from malignant melanoma. Their medical history confirmed that the removal of cutaneous lesions of the frontal, temporal or eyelid skin had been performed presumedly without histologic examination. Disease staging was assessed as p-T0N1M0. Parotidectomy was performed in all cases without complications, and DTIC was given in one case. One patient died six months after surgery for metastatic disease, another one died disease-free, the third is available for the follow-up. The Authors recommend parotidectomy for prophylaxis in malignant melanoma more than 0.75 mm in thickness which is within a few centimeters of the parotid gland area. Lymphoscintigram might be useful occasionally.

Adult↗
PubMed1989

Papillary thyroid cancer with unusually aggressive behaviour. Case report.

A 22-year-old woman underwent thyroid lobectomy for papillary carcinoma (follicular variant). Local recurrences 4 and 7 months later, with vascular invasion and extrathyroid spread, required extensive surgery and radiotherapy. Ipsilateral lobectomy with near-total or total contralateral lobectomy is advocated for treatment of papillary thyroid cancer.

Adult↗
PubMedDate not supplied

Use of a new malleable implant as a bone substitute in maxillofacial surgery.

Biocompatible osteoconductive polymer (BOP) has been used since 1979 as a substitute for bone in orthopedic surgery and neurosurgery. To date, in maxillofacial surgery, loss of bone volume as a result of either trauma or osteoporosis has been compensated for by autologous bone onlay graft or subperiosteal apposition grafts of synthetic materials. Neither of these solutions is entirely satisfactory. Autologous bone is subject to reabsorption, requiring initial overcorrection and multiple reoperations to achieve an acceptable result. Preshaped implants of Proplast, Vicryl, Gore-Tex, or silicone do not offer much flexibility, and coral granules and hydroxyapatite are difficult to handle. Finally, all foreign materials can elicit problems with tolerability. In its SP (solution/powder) form, BOP is a paste that can be molded precisely to the required shape, making it ideal for maxillofacial surgery. This study examined the long-term tolerability and facial alterations after implants of BOP in 11 patients who underwent post-trauma and cosmetic surgery.

Adult↗
PubMedDate not supplied

The surgical treatment of spondylolisthesis with transpedicular stabilization: a review of 25 cases.

The present study concerns a series of 25 patients submitted to vertebral stabilization and fusion for the treatment of spondylolisthesis. In all of the cases a transpedicular screw system was used. The Steffee plates and screws system was used in 22 cases; the Cotrel-Dubousset (CD) system was used in 3. The listhetic vertebra was L5 in 14 cases, it was L4 in 11 cases. Based on Meyerding radiographic criteria there were: grade I: 8 cases, grade II: 13 cases, grade III: 4 cases. Instrumented fusion was performed at only 1 level in 20 cases, at 2 levels in 5 cases. Mean follow-up was 29 months. Clinical results were evaluated based on the White criteria. The results were satisfactory in 78% of cases. The present study shows that transpedicular vertebral stabilization constitutes a safe method, offering excellent stability essential to consolidation of fusion.

Adult↗
PubMedDate not supplied

Human articular cartilage in osteoarthrosis. I. The matrix. Transmission electron microscopic study.

The present research has been carried out with the aim of contributing to the understanding of morphological changes in human articular cartilage during osteoarthrosis and to evaluate the usefulness of TEM in this application. Only the matrix was examined in this first phase of study. Fragments from the femoral head of 20 patients subjected total hip arthroplasis, were studied by TEM after treatment with current procedures. The images obtained were considered observing the division of cartilage into superficial, intermediate and deep layers. Patients were divided according to the gravity of their clinical conditions. The least severe forms of pathology seem to involve only the superficial layer, which quickly loses the lamina splendens and may be affected by rarefactions of the matrix, which becomes fissured, while the deep layers are only slightly involved. During the later stages, the pathology progresses with irregularity of disposition and size of the collagen fibres and an increase in the number and size of fissures. The intermediate layer shows architectural disorder in the collagen fibres, even reaching the deep layer. The interfibrillar distance appears greater. As pathology progresses, the superficial layer tends to disappear, while the successive layers undergo progressive alteration in disposition and size of the collagen fibres. Globular aggregations of various dimensions and electron density similar to collagen are present in the deep layer.

Aged↗