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Biomedical subjects

A Mangoni

Publications and source records attributed to A Mangoni.

78 records · Page 5Linked to original sources

Nerve conduction velocity distribution in normal subjects and in diabetic patients without clinical neuropathy. I. Motor nerve.

A computer-assisted collision method to evaluate motor conduction velocity distribution of the ulnar and external peroneal nerves in normal subjects and in insulin-dependent and non-insulin-dependent diabetics without clinical signs of neuropathy is described. Distribution curves were sigmoidally (bimodally) shaped in normal and in insulin- and non-insulin-dependent subjects. In insulin-dependent patients, motor conduction velocity of the peroneal nerves was globally impaired, whereas of the ulnar nerves it was normal. In non-insulin-dependent patients, slower conduction velocity was involved in both nerves.

Action Potentials↗

Nerve conduction velocity distribution in normal subjects and in diabetic patients without clinical signs of neuropathy. II. Sensory nerve.

A new computer-assisted method to evaluate sensory conduction velocity distribution and dispersion of the digital nerve of the middle finger in normal subjects and in type I and type II diabetic subjects without any neurological impairment is reported. Distribution curves were exponentially shaped in normal and in diabetic subjects. In insulin-dependent diabetics, only slower conduction velocity fibers were involved, whereas no significant difference was observed between the non-insulin-dependent diabetic group and the control group.

Adult↗

Electrophysiology of the palmomental reflex in normal and parkinsonian subjects.

The palmomental reflex (PMR), obtained by mechanical stimulation of the skin of the thenar and hypothenar eminences of the hand and recording the surface EMG response from the chin muscles homolateral and contralateral to the side of stimulation, was studied in normal subjects and in a group of akinetic parkinsonians, both de novo and treated. PMR was present in most subjects of both groups. No differences regarding the incidence of the PMR homolateral to stimulation of the thenar eminence was found between controls and patients, and it was non-habituating in both groups. When the hypothenar eminence was stimulated, the PMR was present in about half of the subjects of both groups. PMR was present contralaterally in both normal and patients, whereas bilateral PMR prevailed in parkinsonians. Latency and duration of the reflex were significantly shorter in parkinsonians than in controls. The data are discussed in the light of the pathophysiology of the PMR putative pathways in normal subjects and in Parkinson's disease.

Afferent Pathways↗