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Biomedical subjects

A Manenti

Publications and source records attributed to A Manenti.

At least 91 records · Page 5Linked to original sources
PubMedDate not supplied

Spontaneous rupture of the spleen: report of two cases.

Spontaneous splenic rupture is rare and in most cases occurs in a spleen affected by hematologic, neoplastic, or infectious disease or as a complication of pancreatitis. We report the imaging findings in two cases of spontaneous splenic rupture due to non-Hodgkin's lymphoma and pancreatic pseudocyst.

Aged↗
PubMedDate not supplied

Absence of rejection in cryopreserved saphenous vein allografts for hemodialysis.

Since November 1987, a total of 16 dialysis patients in the authors' Center, received a cryopreserved saphenous vein allograft (CSVA) as "third choice" vascular access. ABO and HLA-A-B compatibilities were determined but not considered. Saphenous veins were cryopreserved in liquid nitrogen for variable periods (1-6 mo), so that there was the opportunity to choose the most suitable in dimension. In February, 1989, a total of 13 patients retained a well-functioning access site, whereas three had died from causes unrelated to CSVA. Because rejection of venous allografts still is debated among angiologists, recipient T lymphocyte subsets (CD3-CD4-CD8 and CD4/8) were examined, as were lymphocytotoxic antibodies, before and on days 15 and 30 after implantation. No evidence of immunologic activation was found. Moreover, in 10 of 16 patients the surgeons subcutaneously implanted a fragment of CSVA, and an immunohistochemical study was carried out using an alkaline phosphatase-antialkaline phosphatase (APAAP) technique and a panel of monoclonal antibodies. Minimal infiltration of the outer layer of adventitia was found, mainly caused by monocyte macrophages (Leu M3+) with few T lymphocytes (CD3+). The authors conclude that rejection is not a major cause of failure in CSVA in dialysis patients.

Aged↗
PubMedDate not supplied

Liquid nitrogen snap frozen saphenous vein for vascular access in dialysis.

In the authors' centers, fresh saphenous veins (FSV) procured from routine saphenectomies have been preferred to synthetic prostheses in cases of difficult vascular accesses (VA) for dialysis. The need for veins of different lengths and diameters prompted them to preserve SV by instantaneous freezing in liquid nitrogen since November 1987. Until now, 59 patients have received 35 FSV and 32 cryopreserved SV (CSV). Actuarial patency rates after 1 year are 82% and 72%, respectively. The 6-keto prostaglandin F1 alpha measured on punches of both veins showed residual production of prostacyclin even in CSV, but this was unresponsive to stimulation by arachidonic acid and bradykinin, or to inhibition by aspirin. In the authors' opinion, despite marked endothelial damage, satisfactory clinical results can be obtained by this very simple and cheap method of storing biologic prostheses for dialysis VA.

Aged↗
PubMedDate not supplied

Transinguinal dissection of the femoral artery for aorto-bifemoral bypass.

The authors report a surgical technique for high approach to the common femoral artery, just below the inguinal ligament, which can be useful in cases of difficult dissection of the femoral region or those with diffuse fibrosis or multiple scars. It is also useful when there is a concomitant inguinal hernia to repair.

Aorta↗
PubMedDate not supplied

Hepatic histological lesions during acute experimental peritonitis in the rat.

During acute experimental peritonitis in the rat, the main histological lesions in the liver are represented by venous stasis in the central lobular vein and in the sinusoids; by glycogen mobilization and intracytoplasmic accumulation of triglycerides in the hepatocytes; by activation and hypertrophy of Kupffer's cells.

Acute Disease↗
PubMedDate not supplied

Experimental acute renal congestion in rat: histological observations.

An experimental model of acute and total venous stasis has been realized in kidney of rat by division of the renal vein. Different grades of histological damage have been observed, from initial interstitial edema with only degenerative changes in tubular epithelium to its final necrosis. On the contrary glomeruli appear less involved.

Animals↗
PubMedDate not supplied

Emergency laparoscopy in multiple trauma patients: experience with 106 cases.

Emergency laparoscopy was successfully used in 106 multiple-trauma and often unconscious patients with blunt abdominal traumas. In 40 cases a negative result avoided any subsequent exploratory laparotomy; two false negative were registered, while a diagnosis of retroperitoneal hematoma was possible in 6 cases.

Abdominal Injuries↗