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Biomedical subjects

A Mamoli

Publications and source records attributed to A Mamoli.

At least 55 records · Page 3Linked to original sources
PubMed1985

Occurrence of pituitary adenoma in craniofacial fibrous dysplasia: a neuroendocrine and neuroradiological case study.

An 18 year old man with fibrous dysplasia of bone and several endocrine abnormalities was investigated. Laboratory tests showed high levels of prolactin, TSH and GH and low levels of testosterone and LH. TRH and GnRH showed normal responsiveness of the pituitary in spite of the high hormonal levels. The circadian rhythms disclosed no abnormalities of hypothalamic control. The neuroradiological study revealed pathological tissue but no positive sign of a pituitary adenoma, although the sella turcica polytomograms did suggest erosion of the floor. Our data are compatible with the presence of a mixed adenoma or adenomas of the pituitary. We emphasize the importance of a correct study, including neuroradiological and neuroendocrine investigations, in patients with fibrous dysplasia of bone.

Adenoma↗
PubMedDate not supplied

Carbamazepine does not affect short-latency somatosensory evoked potentials: a longitudinal study in newly diagnosed epilepsy.

Somatosensory evoked potentials from median nerve stimulation were recorded in 12 patients with newly diagnosed epilepsy, before and after 1 year of treatment with carbamazepine. The plasma concentrations of the drug were consistently within therapeutic range. We assessed the latencies of the early components at the level of the cervical spine (N9 and N13) and on the parietal scalp (P14, N20, P25) and the interpeak latencies (N9-N13, N13-N20, P14-N20). None of the patients presented anomalies in any of the parameters, and there was no significant difference between the patient and control means or between the patient means before and after 1 year of treatment.

Adolescent↗
PubMedDate not supplied

A case of "young stroke" with ICA intracranial occlusion: pathogenetic implication for dissection in migraine.

The case of a "young stroke" affecting a 22 years old man is reported. Essential clinical features were drowsiness, headache, motor aphasia, right hemiparesis and Claude-Bernard-Horner in the left eye. An extensive investigative protocol was carried out which revealed an occlusion of the intracranial left ICA with subsequent recanalization. The possible causes of the stroke (migraine, dissection or combination of both) are discussed and the importance of a complete evaluation of patients of this kind is stressed.

Adult↗
PubMedDate not supplied

Parasympathetic function in Huntington's disease.

Parasympathetic function in 7 Huntington's chorea patients with a duration of the disease ranging from 1 to 20 years, was evaluated by studying R-R intervals during quiet and deep breathing and Valsalva manoeuvre. All 7 patients were free of neuropathy, orthostatic hypotension, heart or lung disease and had had no medication for at least 15 days prior to hospitalization. Seven normal subjects served as controls. On the whole, the responses of the Huntington's chorea patients were not significantly different from those of the controls. Abnormal responses to all the tests were received in only one patient and a low R-R variability during deep breathing in the youngest patients. Unlike other Central Nervous System degenerative disorders, in Huntington's disease parasympathetic autonomy seems to be sufficiently preserved.

Adult↗
PubMedDate not supplied

Somatosensory evoked potentials and peripheral nerve conduction velocities in patients on long-term carbamazepine therapy.

The motor and sensory conduction velocities were measured, and the somatosensory evoked potentials were recorded on median nerve stimulation in 20 epileptics on long-term carbamazepine therapy. The plasma drug levels were monitored and found to be consistently within therapeutic range. The electrophysiological study showed that the motor and sensory conduction velocities in the lower limbs were significantly lower than in age-and sex-matched controls, while no significant variation was found in the somato-sensory evoked potentials. There was no correlation between the neurophysiological data and any of the pharmacological data, such as duration of treatment, plasma levels and dose of drug per Kg of bodyweight per day.

Adolescent↗
PubMedDate not supplied

[Evoked potentials in 3 cases of dystrophia myotonica with neuropathic variant].

3 patients with Myotonic Dystrophy (MD) and associated leg motor neuropathy, confirmed in two of them by biopsy of one branch of lateral popliteal nerve, were studied with Multimodality Evoked Potentials. Abnormalities of VEPs and BAEPs, in agreement with literature, were found in all patients. Median SEP peripheral conduction velocity, N9-N13 and N13-N20 conduction time were normal. On the contrary, all patients showed reduced lower limb SEP peripheral conduction velocity niloutstanding normal nerve biopsy. These results suggest in MD neurological abnormalities occur outside muscular system, too.

Adult↗