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Biomedical subjects

A Malpani

Publications and source records attributed to A Malpani.

17 recordsLinked to original sources
PubMed1998

A new curved vitreous cutter for managing phakic retinal detachment with proliferative vitreoretinopathy.

In the presence of proliferations anteriorly, adequate excision of the vitreous base is essential. To enable a good vitreous base excision, removal of lens often becomes necessary as it may be damaged while attempting to remove peripheral vitreous. To avoid damage or the need to remove the crystalline lens we have used a new modified curved vitreous cutter along with a wide angle observation system binocular indirect ophthalmomicroscope (BIOM). Use of BIOM during vitreous surgery enables easy viewing of the retinal periphery without the need for scleral depression. Sclerotomies are made as for any regular three-port vitrectomy procedure and the vitrectomy is carried out using the curved vitreous cutter, including the vitreous base, avoiding damage to the crystalline lens. The modified curved vitreous cutter is helpful in removing the peripheral vitreous without damaging the crystalline lens, giving the patient the advantage of intraocular lens implantation at a later date.

Equipment Design↗
PubMed1995

Postsurgical endophthalmitis: diagnosis and management.

Infectious endophthalmitis following intraocular surgery is a complication that could cause severe visual loss or loss of the eye. The categorisation of the event that led to intraocular infection will help the clinician to predict the infectious agent and begin appropriate therapy. Most of the cases of postsurgical endophthalmitis are seen following cataract surgery. It is important for all ophthalmologists, irrespective of specialisation and areas of interest, to be familiar with the management of endophthalmitis. This review briefly describes the facets of clinical and laboratory diagnosis, pathology, and management. While the different viewpoints in the management of endophthalmitis are mentioned in appropriate places, more attention is paid to present a rational approach to the management of endophthalmitis.

Anti-Bacterial Agents↗
PubMed1992

Routine prophylactic oophorectomy at the time of vaginal hysterectomy in postmenopausal women.

Our experience with the routine removal of ovaries at the time of vaginal hysterectomy for 150 postmenopausal women is presented. The records of these women were compared with 200 women who underwent simple vaginal hysterectomy. The additional step of vaginal oophorectomy did not add to the morbidity of vaginal hysterectomy, and it is recommended that routine oophorectomy be considered for postmenopausal women having a vaginal hysterectomy.

Female↗
PubMed1992

Simplifying assisted conception techniques to make them universally available--a view from India.

In-vitro fertilization and related assisted conception techniques are beyond the reach of most infertile couples in India because they are so expensive. Recent innovations such as the use of the natural cycle, the techniques of gamete intra-Fallopian transfer, intravaginal culture and transcervical oocyte--sperm transfer, vaginal ultrasound-guided oocyte retrieval and the availability of ready-to-use culture medium have helped to simplify assisted conception. Research today should focus on further developing these techniques so that better pregnancy rates can be achieved with them. These simplified inexpensive assisted conception techniques can then be adapted for conditions in the developing world, so that infertile patients the world over can benefit from them.

Carbon Dioxide↗
PubMed1989

New technique for managing second trimester intrauterine fetal death.

In this study, a new method for terminating second trimester pregnancies complicated by intrauterine fetal death is analysed. The technique consisted of a combination of extraamniotic ethacridine lactate with intramuscular sulprostone (16-phenoxy-omega-17,18,19,20 tetranor PGE2 methyl sulfonylamide). Objective documentation of the efficacy of this method was obtained by continuous monitoring of intrauterine pressure in two patients. The method was found to be simple, safe, cheap and effective and deserves increased acceptance.

Abortifacient Agents↗
PubMed1988

Second trimester abortion with ethacridine lactate plus carboprost--which is the best time to administer the carboprost?

Extra-amniotic ethacridine lactate plus intramuscular prostaglandin has become a popular method for terminating second trimester pregnancies. In this study, intrauterine pressure was continuously monitored in order to objectively compare the efficacy of 3 different times of administration of Carboprost (15-methyl PGF2 alpha) - at 2 hours, 4 hours and 8 hours after the instillation of ethacridine lactate. The best results were obtained with the administration of Carboprost 8 hours after the instillation of the extra-amniotic ethacridine lactate. The synergistic effect of ethacridine lactate and Carboprost is optimal after this time. This is probably because the ethacridine lactate will have produced sufficient cervical ripening to ensure optimal efficacy of the prostaglandin-induced uterine contractions in expelling the products of conception.

Abortifacient Agents↗
PubMed1988

Role of sonography in trichobezoars.

Three cases of trichobezoar (12/F, 5/F, and 35/M) are reported. All patients presented with an epigastric mass and the diagnosis was not suspected clinically. They were referred for sonography which revealed a hyperechoic curvilinear dense strip at the anterior margin of the lesion associated with marked acoustic shadowing and no through transmission. Similar findings were noted in all three cases. In vitro ultrasound scans performed on the operated specimen in one case confirmed that the sonographic findings were the result of the trichobezoar mass. Diagnosis was confirmed in all the cases by barium meal and surgery.

Adult↗
PubMedDate not supplied

Endometrial hyperplasia: value of endometrial thickness in ultrasonographic diagnosis and clinical significance.

The records of 90 patients with histologically proven endometrial hyperplasia (EH) were reviewed retrospectively. Eleven of these patients had pelvic ultrasound examinations available. These were compared to the pelvic ultrasound examinations of 19 patients with a histologically normal endometrium, available in 126 consecutive patients seen over the same period of time. Patients with EH had a mean endometrial thickness of 18.8 mm (range 8 mm to 45 mm) vs 5.4 mm (range 2 mm to 10 mm) in the control group. This difference in thickness was statistically significant (p much less than .01). The specificity and sensitivity of endometrial thickness in the diagnosis of EH were 100% and 81%, respectively, when 10 mm was taken as the upper limit of normal. Ultrasonographically demonstrable endometrial characteristics can differentiate EH from normal endometrium in a great majority of cases. The clinicopathological significance of EH is discussed.

Adult↗