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Biomedical subjects

A Maitland

Publications and source records attributed to A Maitland.

30 records · Page 2Linked to original sources

Aorta-right atrial fistula: an unusual complication of ascending aortic dissection.

Ascending aortic dissection complicated by aorta-right atrial fistula is a very rare occurrence. The patient may present with atypical clinical findings such as a continuous murmur or atrioventricular block, making the diagnosis difficult. Surgical repair is straightforward unless the correct diagnosis is missed, in which case there may be difficulties during the initial period of cardiopulmonary bypass. This report deals with the successful management of a 67-year-old man with this condition.

Aged↗

A rearing system for colostrum-deprived neonatal piglets.

A system for the artificial rearing of colostrum-deprived neonatal piglets is described. A total of 443 piglets in 6 batches was reared. Each piglet, immediately after birth was placed in a separate incubator which was ventilated with heated filtered air. Piglets were fed hourly by an automatic system and were offered a liquid milk substitute. The mean survival rate up to the time piglets were transferred out of the rearing unit at 2 weeks of age was 78 +/- 7%. The mean daily live weight gain up to 2 weeks of age was 148 +/- 16 g/day and the dry matter intake over the same period was 154 +/- 10 g/day per piglet.

Animal Feed↗

A method of treating serous fluid leak from a polytetrafluoroethylene Blalock-Taussig shunt.

A 3 1/2-year-old girl with complex cyanotic congenital heart disease underwent palliation with a modified Blalock-Taussig shunt, for which a 6 mm polytetrafluoroethylene graft was used. Seroma formation with serous leakage occurred. Two periods of conservative management failed. At reoperation, treatment of the graft with intraluminal "fibrin glue" resulted in immediate resolution of the leak.

Blood Vessel Prosthesis↗

Enzyme-linked immunosorbent assay for the measurement of immunoglobulin G concentrations in porcine plasma and colostrum.

An enzyme-linked immunosorbent assay is described for the estimation of porcine immunoglobulin G in either colostrum or plasma samples. The inter-assay coefficient of variation was 9.1 per cent and the intraassay coefficient of variation was 7.2 per cent. The repeatability or intra-class correlation coefficient of the assay was 0.9. The assay proved to be a sensitive, inexpensive and rapid method for assessing the immune status of pigs.

Animals↗

Changing the operative strategy for thyroid cancer by node sampling.

One hundred fifty patients underwent thyroid surgery from 1979 to 1981, of whom 48 showed cancer for a 32 percent rate. In eight patients (16 percent), obvious clinical nodal disease was treated with modified neck dissection. Of the remaining 40 patients, internal jugular node sampling was carried out in 33, and revealed microscopic metastatic cancer in 12 patients who then underwent appropriate neck dissection. Node sampling increased our yield of nodal metastases from 16 to 42 percent, permitted one-hospitalization treatment, and afforded our patients the possibility of complete cancer control and prevention of the emergence of future recurrent disease. It is recommended that node sampling be incorporated into the operative strategy for thyroid cancer to permit intelligent selection of patients for modified neck dissection.

Adult↗

Macro--creatine kinase 2: a possible marker of gastrointestinal cancer?

Creatine kinase (CK) is an enzyme found in many body organs. It is used clinically in the diagnosis of myocardial infarction. Recently an atypical isoenzyme, macro-CK2, not found in the sera of healthy individuals, has been reported in patients with gastrointestinal malignancies. This study is a report of our findings in serum samples obtained from 200 patients from November 1981 until December 1982. Twenty-eight patients had gastrointestinal complaints but did not have malignant disease. One hundred seventy-two patients had malignancy. Samples of serum were studied for macro-CK2 with a standard laboratory agarose gel electrophoresis technique. The tests were done without knowledge of the patients' diagnoses. The results show no detectable macro-CK2 in sera from patients without malignancy. It was present before operation in nine of 13 patients with colorectal cancer and 16 of 21 patients with metastases from colorectal cancer or gastric cancer. This preliminary study suggests that the presence of macro-CK2 in serum may be an indicator of malignancy of the gastrointestinal tract and in particular of colorectal cancer.

Adult↗

Arthroscopic findings in the frozen shoulder.

We report 24 patients with a clinical diagnosis of frozen shoulder who underwent an arthroscopic examination and were reviewed. A painful and stiff shoulder was present for an average of 8 months prior to the arthroscopy. The examinations were performed under general anesthesia and through a posterior route. The capacity of the genohumeral joint was measured by infiltration of physiologic saline and it was subnormal in almost 60% of the cases. Only 1 rupture of the rotator cuff was noted which had been previously demonstrated by arthrography. A torn long head of biceps was identified in 2 cases. No intraarticular adhesions were noted. These observations implicate an extra-articular cause for this clinical entity.

Adult↗