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Biomedical subjects

A M Wolff

Publications and source records attributed to A M Wolff.

24 records · Page 2Linked to original sources

Family-planning clinics and educational programmes--a rural experience.

Although family-planning clinics are numerous and well-accepted in most Australian capital cities, such clinics have been difficult to establish in some Victorian rural towns. One such clinic was established at a rural base hospital in a Victorian town in 1984. The history of the clinic's development and its mode of operation are discussed. The profiles of 157 consecutive new patients who attended the clinic are presented. Comparisons are made with the patient profiles from a Melbourne family-planning clinic. The clinic also provides a separate weekly educational programme. The effect of the educational service in attracting patients to the clinic also was evaluated. Over all, it was concluded that the successful establishment of this clinic has been a result of the appointment of female medical and nursing staff members, the support of the local base hospital, an active media campaign and the development of a separate and concurrent educational programme that was conducted by clinic staff members. It is recommended that these factors be considered in the future development of such clinics in rural areas.

Adolescent↗

Osteotomy of the tibial tubercle during total knee replacement. A report of twenty-six cases.

The cases of twenty-four patients who had twenty-six osteotomies of the tibial tubercle in conjunction with total knee replacement were analyzed with regard to complications and technical considerations. The patients were followed for a minimum of two years (average, three years and six months). Major complications related to the surgical technique occurred in 23 per cent of the knees and complications not related to the technique, in an additional 8 per cent. Rheumatoid arthritis and a history of at least one previous operation about the knee were predisposing factors for these complications.

Adult↗

Photoaffinity reagents for use with pepsin and other carboxyl proteases.

Two compounds have been designed to serve as photoaffinity reagents for use with carboxyl proteases. 1,2-Epoxy-3-(4'-azido-2'-nitrophenoxy)propane has been synthesized and shown to react with porcine pepsin in the same fashion as the traditional inhibitor 1,2-epoxy-3-(p-nitrophenoxy)propane, while p-azidophenacyl bromide is similar to other phenacyl bromides in its reaction with pepsin. In combination with p-azido-alpha-diazoacetophenone, previously shown to resemble alpha-diazo carbonyl reagents in its reaction with pepsin, photoaffinity analogs are now available for all three of the widely-used carboxyl protease inhibitors.

Affinity Labels↗

Reticulum cell sarcoma (histiocytic lymphoma) of the orbit.

The clinical and pathologic features of 13 patients with biopsy-proven reticulum cell sarcoma of the orbit are reviewed. All of the patients were adults, in contrast to many previous reports that have emphasized how common this tumor is in children. Eight patients presented with proptosis and without prior diagnosis of lymphoma, and 5 patients developed orbital deposits in the course of a known systemic lymphoma. Of the 8 patients whose orbital biopsies established the diagnosis, 4 were found concomitantly to have other sites of disease, and 4 patients developed other evidence of lymphoma from 2 to 15 months after orbital biopsy. None of the cases in this series was interpreted as a primary orbital lymphoma. The histopathologic findings, the problem of histogenesis, and the need for systemic staging of cytologically malignant orbital lymphoma are discussed.

Adult↗