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Biomedical subjects

A M Wodowosow

Publications and source records attributed to A M Wodowosow.

8 recordsLinked to original sources
PubMed1995

[Circular figures surrounding the macula of patients with albinism in chromato-ophthalmoscopic examination with transformed light].

Examination of the fundus oculi in redfree polarized light carried out in 19 patients (12 with albinism and 7 with albinotic type of fundus oculi) have revealed for the first time peculiar ringlike figures. Since there is no evidence that these figures are formed by retinal folds, the authors suppose that it may be the result from light wave interference. Light waves of the fundus oculi may be reflected not only by the internal limiting membrane but also by Bruch's membrane. These waves overlapping each other form a figure identical to Newton's interference rings, since the thickness of the retina is increasing from the foveola towards the periphery. The ringlike figure in the center of the fundus oculi may be regarded as an additional clinical signs of albinisms of the fundus oculi.

Adolescent↗
PubMed1991

[Comprehensive study of the iris in transformed light in simple glaucoma].

Complex examination of the iris under light transformed by various methods - iridochromoscopy with iridochromophotography, transillumination in red light, and fluorescein angiography - was performed on 26 eyes of patients with simple glaucoma and 24 normal eyes of subjects aged between 42 and 76 years. All the methods employed revealed iris changes in 100% of the simple glaucoma cases. The differences found between the study group and the controls were significant (P = 0.01). A highly positive correlation was found between the results of iris fluorescein angiography and iridochromoscopy with iridochromophotography (r = 0.932; P = 0.0005), as well as between the results of iris fluorescein angiography and transillumination in red light (r = 0.921; P = 0.0005). Complex examination of the iris under transformed light showed the most typical changes in simple glaucoma to be exogenous pigmentation of the pupillary and ciliary regions, partial or complete destruction of the pupillary margin, and stromal atrophy affecting the pupil or the entire iris. Defects and thinning of the posterior iris pigment layer, iris vessel permeability disorders associated with hypoperfusion and microneovascularization in the lesser circle and the ciliary region were also found.

Adult↗
PubMed1991

[Iridochromoscopy].

The author has developed methods for examination of the iris in the light of different spectral composition. The studies have revealed that employment of colored filters in biomicroscopy and photography of the iris helps detect the pathologic shifts undetectable by routine examination. Examinations in polychromatic and changing in succession monochromatic light help carry out a sort of spectral analysis of the clinical features of iridal diseases.

Glaucoma↗
PubMed1982

[Further observations on the application of the campimetric method for measuring individually tolerated intraocular pressure in glaucoma].

The results of campimetric investigations performed in 127 eyes (83 patients) are presented. The vertical diameter of the blind spot and intraocular pressure were measured several times before and after oral intake of a dose of glycerol combined with ascorbic acid. The tonometric value obtained when the blind spot is smallest is considered the individually tolerated level of intraocular pressure. This tolerable pressure was determined in 105 eyes. In the overwhelming majority of the cases (95 eyes) the initial IOP values were within the standard (not exceeding 27 mmHg), according to the present glaucoma classification. However, in 64 eyes the IOP level approached the upper limit of the standard and only in 31 eyes was it between 18 and 22 mmHg. In contrast, the individually tolerated intraocular pressure in 99 eyes (94.3%) shifted to a level of between 18 and 22 mmHg and only in six cases. (5.7%) did the intraocular pressure also remain at the upper limit of the standard after intake of glycerol combined with ascorbic acid. These data show that the individually tolerable intraocular pressure, which does not interfere with the blood circulation in the retina and optic nerve, is in the 18-22 mmHg range in most patients. Under these conditions the vertical diameter of the blind spot (measured at a distance of 1 m with an object 2 mm in diameter) does not exceed 12 cm. This simple method of determining the individually tolerable method of determining the individually tolerable intraocular pressure can be used in any ophthalmological practice.

Glaucoma↗
PubMed1980

[Deep and hidden drusen of the optic nerve as cause of pseudopapilledema (author's transl)].

We examined 160 patients with pseudopapilledema caused by deep and hidden drusen. The advantages of ophthalmochromoscopy versus fluorescein angiography in diagnosing deep drusen are demonstrated. The role of fluorescein examination in differentiating pseudopapilledema from genuine papilledema is pointed out. After many years of observation of patients suffering from drusen and of their relatives, and by studying the histologic data, the dynamics of the process were revealed. A classification of drusen according to depth of location is suggested. Hidden, deep and amputated drusen are distinguished. The conclusion is that deep and hidden drusen are the most frequent cause of pseudopapilledema.

Adolescent↗
PubMed1979

[The campimetric method for measuring the individually tolerated intraocular pressure (Ptl) in glaucoma (author's transl)].

Standard values of the intraocular pressure, as an average result of mass examinations, need not be valid in the actual case. So the upper limit of the intraocular pressure for a hypertonic patient may be higher than in persons with arterial hypotonia. In order to achieve an individual approach A. M. Vodovozov introduced in 1975 the notion of tolerable intraocular pressure (Ptl) which may be determined by means of campimetry and perimetry, or using hemodynamic and electrophysiological methods. Here the campimetric method of determining the individually tolerable intraocular pressure (Ptl) is described. The size of the blind spot (namely the vertical diameter) and the pertinent intraocular pressure are measured several times (every half an hour), in the course of which the effect of an oral dose of glycerol combined with ascorbic acid is observed. That tonometric value which coincides with the minimal size of the blind spot is considered as the individually tolerable level of intraocular pressure. The campimetric investigation of 98 eyes in 52 glaucomatous patients showed that the tolerable intraocular pressure may be above as well as below the standard. This aids in ordering the appropriate treatment and in preventing the loss of ocular function in glaucomatous patients.

Ascorbic Acid↗