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Biomedical subjects

A M Sonneland

Publications and source records attributed to A M Sonneland.

3 recordsLinked to original sources

Luteinizing hormone-releasing hormone downstaging of clinical stage C prostate cancer.

A total of 7 patients with clinical stage C prostate cancer determined by digital rectal examination, transrectal ultrasonography, radionuclide bone scanning and serum prostatic acid phosphatase determination was treated with luteinizing hormone-releasing hormone analogues for 2 to 5 months in an attempt to downstage the disease. Although substantial decreases in prostate specific antigen level and prostatic volume occurred, only 2 patients experienced pathological downstaging of disease. We conclude that luteinizing hormone-releasing hormone therapy for downstaging of clinical stage C prostatic cancer is of limited value.

Aged↗

Extravesical ureteroplasty.

The results of extravesical ureteroplasty (Lich-Gregoir technique) for primary extravesical reflux in 62 children with 82 refluxing renal units are evaluated. Postoperative radiograms revealed persistent reflux in 5 (6.1 per cent) and obstruction in 1 (1.2 per cent) of the renal units. Of 7 patients in whom bilateral reflux had been noted previously but who had unilateral reflux at the time of operation, unilateral repair resulted in absence of reflux on the contralateral side in 6. The favorable success rate, low morbidity and median 5-day hospitalization support the use of extravesical ureteroplasty for uncomplicated reflux.

Adolescent↗