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Biomedical subjects

A M Romanenko

Publications and source records attributed to A M Romanenko.

At least 55 records · Page 3Linked to original sources
PubMed1982

[Chronic cystitis in the aspect of its relationship with precancerous conditions].

A morphological analysis of biopsy specimens from 32 patients with chronic cystitis allowed proliferative and nonproliferative forms of the disease to be distinguished. Chronic cystitis with von Brunn cell nests, cystic and glandular cystitis comprise different stages of the same pathological process which shows no trend for malignization. They may be considered to be the background diseases in the development of the bladder cancer. Vesical leukoplakia tends to malignancy and should be considered as a facultative precancer. Structural-metabolic reorganization in the connective tissue of the submucous layer with impairment of the vessel wall permeability regularly precedes the development of proliferative changes in the epithelial layer of the bladder wall.

Cell Transformation, Neoplastic↗
PubMed1981

[Ultrastructural characteristics of seminoma and embryonal cancer of the testis].

Twenty-three germ cell tumors of the testis were investigated. Electron microscopic examinations of four seminomas and four embryonal carcinomas revealed cells of different degrees of differentiation. Tumor cells of seminoma acquired the ultrastructural features of the cells of developing seminal epithelium whereas in embryonal carcinoma there was a pronounced tendency of formation of mature tissues of teratoma. These data confirmed the cytogenetic resemblance of seminoma and embryonal carcinoma originating from the seminal epithelium which could undergo malignization at different stages of development. The latter predetermined diverse direction of differentiation in germ cell tumors of the testis.

Adolescent↗
PubMed1978

[Late results of the combined treatment of bladder cancer depending on the histological form of the tumor].

The writers present an analysis of the remote results of the combination therapy in 208 patients with cancer of the urinary bladder, depending on the histological form of the tumor. Radical surgery was performed in 193 patients, palliative--in 15. All types of surgical intervention were associated with radiotherapy in the pre- and postoperative period. The survival for 3 years and longer was noted in 153 patients, for 5 years and longer--in 69. Transitional-cell papilloma is characterized by the most favourable prognosis.

Adult↗
PubMed1976

[Hyperplastic foci in chemical carcinogenesis].

Morphological, histochemical and biochemical perculiarities of liver hyperplastic nodules induced by different chemical carcinogens are regarded. The presence of basophylic atypical cells in the hyperplastic nodules, the possibility of transplantation of some nodules, the irreversibility of some morphological and biochemical lesions in these allows to designate hyperplastic nodules as a neoplasm. Enzyme and isozyme patterns in hyperplastic vesicles, the appearance of alpha-fetoprotein in these, and some other metabolic findings suggest biochemical disdifferentiation occurring in the vesicles. These findings suggest that cells of hyperplastic nodules are intermediate between normal and malignant cells in the course of neoplastic transformation.

2-Acetylaminofluorene↗