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Biomedical subjects

A M Peters

Publications and source records attributed to A M Peters.

276 records · Page 16Linked to original sources
PubMed1980

Radionuclide distribution following injection of 111Indium-labelled platelets.

Platelets labelled with 111In displayed similar survival curves after incubation with 111In-oxine in plasma, plasma-saline and dextrose saline media. The use of autologous red cells to cushion platelets during high-speed centrifugation facilitated platelet resuspension without greatly affecting the duration of the labelling procedure. Quantitative scanning after reinjection of labelled platelets in haematologically normal subjects showed that, initially, splenic indium amounted to about 35% of the injected dose and hepatic indium about 12%; these levels rose only slightly over the subsequent duration of the platelet life span. Subtraction of the signal from indium in platelets thought to be normally pooled within the spleen from the total indium signal gave splenic indium uptake curves which reflected splenic platelet destruction. Initially, the sum of indium levels in spleen, liver and blood equalled 100% of the dose. Thereafter, the sum fell progressively at a rate thought to be approximately equal to the rate of bone marrow uptake.

Blood Platelets↗
PubMed1978

[Veterinary herd management programme on a beef bull farm (author's transl)].

A report on herd management advice on a beef bull farm by a multidisciplinary committee over a three-year period. Eight groups, each consisting of approximately ninety-six bulls (781), were fattened and delivered. Fattening of the calves was started at the age of one week and they were delivered at the age of seventy weeks. For the first ten weeks, they were individually housed in rearing pens, then they were kept in groups of eight in housings with slatted floors. Studies were done to see whether waste matter of the potato-processing industry could be turned into useful material in this manner. This was found to be the case, provided sufficient attention was paid to the other constituents of the ration. Veterinary problems consisted in diseases of newborn animals, indigestion accompanied by tympanites, respiratory diseases, foul in the foot and injuries. Minor problems were lice, loss of cuds, infectious keratoconjunctivitis, trichophytosis, urinary calculi, cysticercosis, cerebrocortical necrosis and abscesses in organs. The total proportion of deaths and rejects was 7.8 per cent, 2.6 per being due to mortality. A classification by cause and age was established. Moreover, the relationship between differences in growth and particular forms of disease was studied. This relationships could be shown to be present in some cases but there also were marked differences which could not be accounted for on the basis of patient administration. On the whole, the state of health was highly satisfactory.

Animal Feed↗
PubMedDate not supplied

Scintigraphic imaging of renal function.

Scintigraphic imaging of renal physiology can be achieved by gamma camera planar imaging, single photon emission computerised tomography (SPECT) or positron emission tomography (PET). Physiological information about the kidney usually requires dynamic imaging, although for some applications imaging may be static. Individual kidney renal blood flow can be measured from dynamic gamma camera imaging, although with PET it is possible to measure regional renal perfusion. Measurement of individual kidney glomerular filtration rate (GFR) is performed routinely with Tc-99m-diethylene triamine pentaacetic acid (DTPA), but information about GFR on a regional basis, and measurement of regional filtration fraction, require PET. Manoeuvres which interfere with renal physiology, such as captopril renography, may also yield useful diagnostic information.

Captopril↗
PubMedDate not supplied

Uses of labelled white cells.

In addition to an established clinical role, labelled white cells have great potential for clinical research. This review will therefore outline the clinical use of labelled white cells and briefly consider their contribution to developments in clinical science.

Bacterial Infections↗