Biomedical subjects

A M Norbut

Publications and source records attributed to A M Norbut.

7 recordsLinked to original sources

PubMed1981

Primary glioblastoma multiforme of the pineal region with leptomeningeal metastases: a case report.

The incidence of primary intracranial glioblastoma multiforme originating in the pineal region is exceedingly rare. Diffuse leptomeningeal involvement, including spinal subarachnoid metastases, by a primary glioblastoma multiforme of the pineal region has not been reported. A report of a case of primary glioblastoma multiforme of the pineal region accompanied by diffuse leptomeningeal and nodular spinal subarachnoid metastases is presented. Extensive evaluation of the complete neuraxis, including histologic examination, in all cases of primary pineal neoplasm appears to be of both diagnostic and therapeutic value.

Adult↗

PubMed1981

Microcomputer reporting and information system for microbiology.

A computerized reporting and information system for microbiology employing a relatively inexpensive microcomputer is described. A comprehensive approach to accessioning and result entry for microbiology is presented. A daily laboratory worklist is generated for each work area, providing the responsible technologist with information on previously processed specimens. Manipulation of patient and specimen information permits the performance of various functions, including the generation of billing reports, workload statistics, quality-control summaries, epidemiologic surveys, and cumulative reports. The employment of many user-definable data lexicons allows optimal use of disk space while affording rapid information retrieval. Data file maintenance is automatically accomplished by the system, requiring no user intervention.

Computers↗

PubMed1980

Lymphoepithelioid cellular lymphoma (Lennert's lymphoma) in association with malignant lymphoma, histiocytic type.

The present case is unusual in that it demonstrates the presence of the histologic pattern of Lennert's lymphoma in a patient who had a 14-year history of recurrent reticulum cell sarcoma (histiocytic lymphoma). This particular lesion also exhibits clinical and pathologic similarities to angioimmunoblastic lymphadenopathy and malignant lymphoma of peripheral T-lymphocyte origin. Whether the appearance of Lennert's lymphoma in this patient represents a regression of the previous reticulum cell sarcoma (histiocytic lymphoma) to a more benign form, a response to therapy, an alteration in the immune system, or a new lymphoreticular malignancy remains to be answered.

Aged↗

PubMed1980

Pathology accessioning and retrieval system with encoding by computer (PARSEC). A microcomputer-based system for anatomic pathology featuring automated SNOP coding and multiple administrative functions.

A pathology accessioning and retrieval system with encoding by computer (PARSEC) has been developed, employing a relatively inexpensive microcomputer. PARSEC performs a variety of administrative functions for anatomic pathology, including accessioning of surgical specimens, storage of patient demographic information, editing, retrieval, and archiving of patient data, as well as CAP (college of American Pathologists) workload units, billing, and inventory functions for histopathology. In addition, appropriate gross and microscopic descriptions and pathologic diagnoses can be entered into the system by a text editor. Automatic assignment of SNOP (Systematized Nomenclature of Pathology) codes, is accomplished via an online SNOP lexicon, allowing the ultimate generation of completed surgical pathology reports. The data base management system employed makes optimum use of disk storage space, while permitting rapid data retrieval. Data file maintenance is automatically accomplished by the system, requiring no user intervention.

Computers↗

PubMed1980

Workload recording by microcomputer.

Workload recording as designed by the College of American Pathologists has proven to be an invaluable aid in the assessment of overall laboratory operation. The administrative information derived from the compilation of these workload statistics is utilized to provide effective and these workload statistics is utilized to provide effective and efficient laboratory management. A microcomputer-based system for the pathology department that permits the accumulation of daily raw workoad data is descirbed. A monthly cummulative summary report is subsequently produced, complete with computer-derived College of American Pathologists workload units.

Computers↗

PubMed1980

Quality-control statistical interpretation by microcomputer.

A comprehensive summary report of quality-control data is of great value in monitoring the accuracy and precision of the clinical chemistry laboratory. This report allows a retrospective appraisal alerting laboratory personnel to possible test control material degradation or instrument malfunction. A microcomputer-based program package is described, designed to reduce the errors and lengthy preparation inherent in the manual generation of such a report. Quality-control summary data is automatically compared with a predefined set of statistical criteria, and any aberrant values are flagged, thus eliminating subjective and nonuniform data interpretation. Statistical comparisons include: number of control points, delta mean, delta standard deviation, standard deviation index, and F-ratio. The summary report is well accepted by the laboratory staff, and its incorporation into the decision-making process allows for an efficient, critical, and uniformly rigorous examination of analytic proficiency.

Chemistry, Clinical↗

PubMed1980

Opportunistic pneumonia caused by a new acid-fast bacterium.

An 80-year-old black woman with a clinical diagnosis of unclassified malignant lymphoproliferative disease experienced acute pneumonia four days after chemotherapy was begun. Open lung biopsy revealed acute suppurative pneumonia with dense neutrophilic alveolar infiltrates but without granulomas or caseous necrosis. Numerous intra- and extracellular gram-negative bacilli were present, some of which were acid-fast. Routine bacterial, fungal, and mycobacterial cultures were negative. The organism was successfully cultivated by embryonated egg inoculation with subsequent transfer to buffered charcoal yeast extract agar. Serologic studies using the indirect fluorescent antibody technic confirmed the presence of an organism recently described as the "Pittsburgh pneumonia agent," further suggesting that this particular organism is a significant cause of suppurative pneumonia in the immunocompromised host.

Aged↗