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Biomedical subjects

A M Nikitin

Publications and source records attributed to A M Nikitin.

At least 109 records · Page 6Linked to original sources

[Diffuse polyposis of the large intestine as a precancerous condition].

In 86 (49.4%) of 173 patients cancer of the colon of various localizations against the background of diffuse polyposis was diagnosed, rectal involvement being noted in 50%, cancer involvement of the cecum involvement of the cecum and ascending colon--in 5.4% and 7.2% accordingly. These data made it possible to revise an existing concept of preservation of the rectum in radicalsurgery for diffuse polyposis in favour of remaining right portions of the colon.

Adolescent↗

[A comparative study of nonsurgical methods in the treatment of hemorrhoids].

The authors conducted comparative appraisal of the results of treatment of hemorrhoids in 3 groups of patients at a higher surgical risk in 1989-1990. Group 1 consisted of 79 patients given the traditional nonoperative treatment. Group 2 was made up of 17 patients in whom the hemorrhoidal nodes were ligated by means of latex rings. Forty-three patients of group 3 were treated by the traditional nonoperative methods and, in addition, by infrared photocoagulation, 33 at in-patients and 10 at out-patient clinics. The follow-up periods range from 3 to 12 months. The study showed that nonoperative therapy produced a temporary effect, clinical manifestations of hemorrhoids recurred in 100% of patients. In group 2 59% of patients were cured, which is evidence of the pathogenetic substantiation of the method. The treatment, however, in this group was marked by a great number of complications of an inflammatory character. The best effect was produced among patients of group 3; 37 (86%) patients were cured. Thus, the results of comparative analysis of the efficacy of these methods of treatment in patients at a higher surgical risk showed the advantages of infrared photocoagulation over nonoperative treatment and ligation of hemorrhoids with latex rings. The method of infrared photocoagulation is technically simple, convenient, and can be applied both in in- and out-patient clinics.

Aged↗

[A study of periodicity in the primary structure of spidroin 1 and spidroin 2 from spiders belonging to various species].

Sequences of spidroin 1 and 2 from spiders belonging to various species were analyzed by Fourier analysis. Specific periodical patterns were found in various segments of the sequences. These characteristic periodicities vary within the same proteins as well as between spidroin 1 and spidroin 2 sequences. It is possible that alterations in periodicity help to recognize contact sites between the molecules. Spidroins of 2 type have similar sequence structure consisting of four parts with a particular periodical pattern. These parts are a constant C-terminal part, a long-periodical part, a short-periodical part, and a constant N-terminal part.

Amino Acid Sequence↗

[Data on a study of a natural focus of sandfly fever in Sevastopol during 1945-1988].

Sandfly [correction of Mosquito-borne] fever in Sevastopol was of a marked season character (June-September), with maximum cases registered in August. The morbidity curve corresponded to the sandfly [correction of mosquito] number curve, lagging behind it because of the incubation period. Since 1947 DDT and hexachlorane, having a lasting effect (40-50 days), have been widely used for sandfly [correction of mosquito] control. This was accompanied by intensive improvement of the living conditions in the city, regular sanitation and deratization. As a result of the above measures sandfly [correction of mosquito-borne] fever has not been registered in the city since 1954. The number of sandflies [correction of mosquitoes] reduced drastically, their species composition has changed: in 1959 sandflies [correction of mosquitoes] were found in 5.4% of the houses examined and in 1988, in 0.16% of houses. Since 1958 only 2 (Phlebotomus papatasii Scop and Ph. major Ann.) out of the former 7 species have been caught. Each species strives for self-preservation. Therefore, epidemiological survey of the former foci and sandfly-control [correction of antimosquito] measures are to be performed annually not to permit recovery of sandfly [correction of mosquito] population and repeated epidemics of sandfly [correction of mosquito-borne] fever.

Animals↗