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Biomedical subjects

A M Lucon

Publications and source records attributed to A M Lucon.

At least 37 records · Page 2Linked to original sources

Adrenal autografts following bilateral adrenalectomy.

Bilateral adrenalectomy followed by immediate transplantation of adrenal slices into muscular tissue was performed in 7 patients with Cushing's disease and 1 with bilateral pheochromocytoma. Patients were followed for 1 to 7 years and only 1 had evidence of a functional graft (serum cortisol level at the lower limit of normality). Low levels of dehydroepiandrosterone sulfate, aldosterone and cortisol were found in the remaining patients. Acute stimulation with adrenocorticotropichormone did not increase either cortisol or aldosterone levels in any patient. We conclude that prospective studies are needed to elucidate factors that could improve the success of adrenal implantation, since the literature shows examples of functional grafts, while the majority of the cases are unsuccessful.

Adrenal Gland Neoplasms↗

Synchronous bilateral carcinoma of the adrenal gland: 2 case reports.

The existence of synchronous bilateral adrenal masses is an uncommon condition except in the relatively more frequent cases of pheochromocytoma or metastatic tumors. Two cases of synchronous nonfunctioning bilateral adrenal cortex carcinoma, removed during the same operation, are described. The patients currently are receiving hormonal supplementation, and were well 16 and 12 months postoperatively.

Adrenal Cortex↗

[Stenosis of the renal artery as a cause of acute renal insufficiency after transplantation].

Eight cases of kidney transplant recipients that developed acute renal failure are described. Arterial renal stenosis was responsabilised for the ARF. One patient was submitted to transluminar angioplasty without success and then operated. This technique was the successful treatment in another patient. Four patient were submitted to surgical correction as first therapeutic approach. Two patients received no specific treatment. From the six treated patients five had good evolution.

Acute Kidney Injury↗

Vesical haemangioma. Report of two cases.

Two cases of vesical haemangioma and a review of the literature are presented. In one of the cases association with cutaneous "Blue Rubber Bleb Nevus" has been found. Vesical haemangioma is a benign tumour, probably of congenital origin, that occurs in young patients. The first symptom is generally haematuria, and diagnosis is confirmed by cystoscopy. The treatment of choice is partial cystectomy, and the most common histologic form is cavernous haemangioma.

Adult↗

Congenital cyst of the seminal vesicle.

A case of congenital cyst of the seminal vesicle in association with an ectopic ureter is presented. The clinical, diagnostic and therapeutic aspects are discussed with special emphasis on the role played by ultrasound and computerized tomography in the evaluation of pelvic pain and painful ejaculation.

Adult↗

Renal autotransplantation in the treatment of hypertensive disease associated with unilateral renal artery stenosis.

Renal autotransplantation was performed on 15 subjects with renovascular hypertensive disease owing to unilateral renal artery stenosis. Kidney survival was achieved in 14 cases. Followup for a minimum of 6 months showed 50 per cent of the patients to be cured, 28 per cent improved and 22 per cent unchanged according to the criteria described herein. There was an 85 per cent cure rate among a subgroup of patients less than 35 years old, with less than 20 months of hypertension and non-atherosclerotic lesions. Plasma renin assay was not found to be a good prognostic indicator as reported previously. In our hands the method showed only a 70 per cent correlation with the final results. Non-atherosclerotic lesions had a better prognosis.

Adolescent↗

Pheochromocytoma treated by laparoscopic surgery.

OBJECTIVE: To evaluate the results of the laparoscopic technique in the treatment of adrenal pheochromocytoma. METHOD: Ten patients, 7 men and 3 women, between 10 and 67 years of age (mean 48) with pheochromocytoma underwent transperitoneal laparoscopic adrenalectomy and were evaluated retrospectively, based on clinical, laboratory, and pathological diagnosis. In all cases there was a solid unilateral adrenal tumor, 5 on the left side and 5 on the right side, whose greater diameter varied from 7 to 80 mm (mean 32). Nine of the 10 patients were chronically hypertensive or had already had hypertensive crises. One patient was normotensive, but presented metabolic alterations suggestive of adrenergic hyperfunction. RESULTS: No deaths occurred in this series. There were two (20%) conversions to open surgery, one due to venous bleeding and one due to the difficulty of dissection behind the vena cava in a patient presenting a partially retro-caval tumor. Surgical time in the 8 non-converted cases ranged from 70 to 215 minutes (mean 136). One patient (10%) received blood transfusion, and another (10%) presented two complications - acute renal failure and a subcutaneous infection. Both had been converted to open surgery. None of the non-converted cases was transfused or presented complications. Hospital discharge occurred between the 2nd and 11th post-operative day (mean 3). The pathological exam of the surgical specimens confirmed the diagnoses of pheochromocytoma in all 10 cases, one of them associated with an aldosterone-producing cortical tumor. CONCLUSIONS: Laparoscopic adrenalectomy for selected patients presenting pheochromocytoma is feasible and provides good results.

Adolescent↗

Disseminated histoplasmosis presenting as bilateral adrenal masses.

Histoplasma capsulatum is a universal dimorphic fungus found mainly in soil contaminated with excrement of birds and bats. Bilateral adrenal masses with massive tissue destruction are a rare primary presentation of disseminated histoplasmosis. As it behaves as an opportunistic pathogen there is a higher susceptibility for dissemination on those patients with immunodeficiency or immunosuppression. We report a case in an elderly diabetic patient with bilateral adrenal enlargement, diagnosed as histoplasmosis only after surgical exploration, with symptoms probably occurring at least 60 years after the original infection. She was successfully treated with itraconazole.

Adrenal Gland Diseases↗