A study of workers exposed to asbestiform minerals in commercial talc manufacture.
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Biomedical subjects
Publications and source records attributed to A M Langer.
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A number of crystalline and optically isotopic inorganic materials are used in the manufacture of reconstituted tobacco sheets. These sheets, used primarily in inexpensive cigars, often contain diatomaceous earth, which exists in part in the silica mineral form cristobalite, a known fibrogen. Diatom fragments with this crystalline form have been observed in the main smoke stream of cigars made with these tobacco sheets.
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The clinical and pathologic features in 11 cases of histiocytosis were reviewed. The were 6 cases of Hand-Schüller-Christian, disease 4 cases of Letterer-Siwe and 1 case of eosinophilic granuloma. The clinical differences among those diseases are outlined. We agree with other authors that the symptoms are related in great measure to the moment of embryonic differentation in which the proliferation occurred. When proliferation is present at an early stage of development of macrophage (promonocyte), a more malignant disease appears than when it occurs at a later stage (macrophage). The treatment of histiocytosis is briefly outlined.
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