Biomedical subjects

A M Kulkarni

Publications and source records attributed to A M Kulkarni.

4 recordsLinked to original sources

PubMed2006

Synthesis and in vitro antibacterial activity of novel heterocyclic derivatives of 18-nor-equilenin.

Syntheses of novel heterocyclic derivatives of 18-nor-equilenin, namely, (12H-11-oxa-17-thia-15-aza-cyclopenta[a]phenanthrene-16-yl)-hydrazine (4a/b) and its fused [1,2,4]triazolo derivatives6H-5-oxa-7-thia-8,9,10a-triaza-pentaleno[4,5-a]phenanthrene (5a/b), 10-methyl-6H-5-oxa-7-thia-8,9,10a-triaza-pentaleno[4,5-a]phenanthrene (6a/b) and tetrazolo derivatives 1-substituted-6H-5-oxa-7-thia-8,9,10,10a-tetraaza-pentaleno[4,5-a]phenanthrene (7a/b) along with their antibacterial activities are reported.

Anti-Bacterial Agents↗

PubMed2001

Prevalence of anti-hepatitis E virus antibodies in different Indian animal species.

Prevalence of IgG antibodies to hepatitis E virus (IgG-anti-HEV) was determined among different animal species from India. Seropositivity varied from 4.4% to 6.9% in cattle, 54.6-74.4% in pigs and 2.1-21.5% in rodents. Of the 44 dogs screened, 10 were positive (22.7%). None of the 250 goat sera tested were found to be anti-HEV positive. Among rodents, over 50% serum samples collected in 1985 from Bandicota bengalensis were positive for anti-HEV antibodies. No evidence of HEV infection was obtained following experimental inoculation of an Indian strain (AKL-90) of HEV into anti-HEV negative pigs and goats. The results document varied prevalence of anti-HEV antibodies in different animal species from India and of inability of Indian pigs and goats to support replication of at least one human strain of HEV.

Animals↗

PubMed1990

Serum zinc and zinc containing enzymes in diabetes mellitus.

Serum zinc and levels of certain zinc containing enzymes like 'lactate dehydrogenase, malate dehydrogenase, alkaline phosphatase and serum insulin were studied in twenty five normal and fifty non insulin dependent diabetics. Zinc estimation was done bp atomic absorption spectrophotometry, insulin by radioimmunoassay and the enzymes by kinetic method. The non insulin dependent diabetic individuals showed significant hypozincaemia (P less than 0.001) associated with significant increase in serum insulin and lactate dehydrogenase level (P less than 0.001). Malate dehydrogenase level was markedly decreased (P less than 0.001). There was no significant variation in serum total proteins, creatinine and alkaline phosphatase levels.

Alkaline Phosphatase↗

PubMed1973

Spinal teratoma.

Explore the source record for details and available documents.

Adult↗