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Biomedical subjects

A M DiGioia

Publications and source records attributed to A M DiGioia.

13 recordsLinked to original sources
PubMed2000

An image overlay system for medical data visualization.

Image Overlay is a computer display technique which superimposes computer images over the user's direct view of the real world. The images are transformed in real-time so they appear to the user to be an integral part of the surrounding environment. By using Image Overlay with three-dimensional medical images such as CT reconstructions, a surgeon can visualize the data 'in-vivo', exactly positioned within the patient's anatomy, and potentially enhance the surgeon's ability to perform a complex procedure. This paper describes prototype Image Overlay systems and initial experimental results from those systems.

Computer Graphics↗
PubMed1998

Computer assisted measurement of cup placement in total hip replacement.

The introduction of image guided systems in total hip replacement surgery provides the ability to plan precisely the alignment of the acetabular cup before surgery, and to perform the surgery according to the preoperative plan. Preoperative planners (interactive computer programs for surgical planning) based on three-dimensional medical images allow planning of optimal placement of implant components based on simulated implant performance. Exact measurement of the cup position during surgery allows precise placement of the cup and accurate measurement of the final position of the cup relative to the pelvis. This measurement is used to evaluate the radiographic techniques for postoperative measurement of cup alignment. Malposition of the acetabular component increases the occurrence of impingement, reduces the safe range of motion, and increases the risk of dislocation and wear. Dislocation of the implant after total hip replacement remains a significant clinical problem. Not fully understanding the interaction between pelvic orientation and final acetabular cup alignment may be one of the main contributing factors in the continued significant incidence of dislocations after total hip replacement. In this study an attempt was made to link the preoperative planning, intraoperative placement, and postoperative measurement of cup placement in total hip replacement using computer assisted techniques.

Acetabulum↗
PubMed1998

Augmented reality and its future in orthopaedics.

Augmented reality is a display technique that combines supplemental information with the real world environment. Augmented reality systems are on the verge of being used everyday in medical training, preoperative planning, preoperative and intraoperative data visualization, and intraoperative tool guidance. The basic technologies of augmented reality are discussed, augmented reality systems currently being used in the medical domain are examined, and some future uses of these systems in orthopaedic applications are explored.

Bone and Bones↗
PubMed1998

The Otto Aufranc Award. Image guided navigation system to measure intraoperatively acetabular implant alignment.

There has been little clinical research to examine the effects of patient positioning and pelvic motion on the alignment of the acetabular implant during total hip replacement surgery. Until now, no tools were capable of accurately measuring these variables during the actual procedure. As part of a broader program in medical robotics and computer assisted surgery, a clinical system has been developed that includes several enabling technologies. The hip navigation system (HipNav) continuously and precisely measures pelvic location and tracks relative implant alignment intraoperatively. HipNav technology is used to gauge current clinical practice and provide intraoperative feedback to surgeons with the goal of improving the precision and accuracy of acetabular alignment during total hip replacement. This system provides surgeons with a new class of image guided measurement tools and assist devices. These tools successfully were introduced into the clinical practice of surgery with results showing the following: (1) There exist unpredictable and large variations in the initial position of patients' pelves on the operating room table and significant pelvic movement during surgery and during intraoperative range of motion testing; (2) current mechanical acetabular alignment guides do not account for these variations, and result in variable and in the majority of cases unacceptable acetabular alignment; and (3) press fitting oversized acetabular components influences the final cup orientation.

Anthropometry↗
PubMed1998

Computer assisted orthopaedic surgery. Image guided and robotic assistive technologies.

Technologies are emerging that will influence the way in which orthopaedic surgery is planned, simulated, and performed. Recent advances in the fields of medical imaging, computer vision, and robotics have provided the enabling technologies to permit computer aided surgery to become an established area which can address clinical needs. Although these technologies have been applied in industry for more than 20 years, the field of computer assisted orthopaedic surgery is still in its infancy. Image guided and surgical navigation systems, robotic assistive devices, and surgical simulators have begun to emerge from the laboratory and hold the potential to improve current surgical practice and patients' outcomes. The goals of these new clinically focused technologies are to develop interactive, patient specific preoperative planners to optimize the performance of surgery and the postoperative biologic response, and develop more precise and less invasive interactive smart tools and sensors to assist in the accurate and precise performance of surgery. The medical community is beginning to see the benefit of these enabling technologies which can be realized only through the collaboration and combined expertise of engineers, roboticists, computer scientists, and surgeons.

Biomedical Engineering↗
PubMed1995

Biomechanics for preoperative planning and surgical simulations in orthopaedics.

Surgical simulations are particularly appropriate for the large volume and expense of joint replacement procedures in orthopaedics. A first generation surgical simulator has been developed to model the implantation procedure for cementless acetabular and femoral components in total hip replacement surgery. The simulator is based upon finite element analysis and predicts the early postoperative mechanical environment that results from a proposed surgery. Since the short- and long-term clinical success of cementless hip replacement components is very dependent upon the initial mechanics of the bone-implant system, such simulations can help orthopaedic surgeons to develop better preoperative plans.

Biomechanical Phenomena↗
PubMed1991

Role of interfragmentary strain in fracture healing: ovine model of a healing osteotomy.

It has been hypothesized that the histological pattern of fracture healing is controlled at least in part by the local mechanical strains in the interfragmentary region. To test this "interfragmentary strain hypothesis," we applied cyclic bending deformations to tibial osteotomies in 11 sheep. An instrumented flexible plate spanning a 1-mm osteotomy gap was deformed to create a gradient of tissue elongation from 10% under the plate to 100% at the opposite cortex. The cyclic deformations were applied three times per minute, 24 h per day, for 1-5 weeks. However, as a result of tissue differentiation, the bone-plate complex increased in stiffness with healing time, resulting in a marked reduction of the gap deformation at approximately 4 weeks. Fracture healing was evaluated using vascular injection of India ink and conventional histology. A nonlinear three-dimensional finite element model of the interfragmentary tissue at the initial stage of healing was used to predict the complex tissue strains. The ingrowth of vascularized soft tissue into the interfragmentary gap, as well as the subsequent differentiation of this tissue, occurred earlier and to a greater degree in regions of lower strain. In contrast, the proliferation of callus tissue was greatest at the periosteal and endosteal surfaces of the cortex opposite the plate. Direct comparison of the finite element predictions with the histology demonstrated that the spatial distribution of bone resorption at the fracture fragment ends directly corresponded to the locations of elevated tissue strain and stress. However, there was no consistent numerical relationship between the magnitude of these local peak strains and the corresponding volume of cortical bone resorption over the bone cross section.

Animals↗
PubMed1991

Periprosthetic fractures of the femur after total knee arthroplasty. A literature review and treatment algorithm.

Supracondylar femur fractures after total knee arthroplasty can significantly alter the quality of knee arthroplasties and provide a challenging problem for the treating surgeon. A review of the literature and an approach to the treatment of these periprosthetic fractures is presented. The predisposing factors, mechanisms of injuries, and characteristics of the fractures are identified. A classification system is proposed based on a modified Neer grading system, the degree of comminution, and the location and character of the fracture. A treatment algorithm is developed and based on acceptable alignments of less than 5 mm translations, angulations less than 5 degrees-10 degrees, minimal rotation, less than 1 cm of femoral shortening, and proper tibiofemoral prosthetic joint alignment.

Algorithms↗
PubMed1986

Three-dimensional strain fields in a uniform osteotomy gap.

Stable internal fixation usually results in a unique histological healing pattern which involves direct cortical reconstruction and an absence of periosteal bridging callus. While it has been suggested that longitudinal interfragmentary strain levels control this healing pattern, the complex, multiaxial strain fields in the interfragmentary region are not well understood. Based on an in-vivo study of gap healing in the sheep tibia by Mansmann et al., we used several finite element models of simplified geometry to: explore modeling assumptions on material linearity and deformation kinematics, and examine the strain distribution in a healing fracture gap subjected to known levels of interfragmentary strain. We found that a general nonlinear material, nonlinear geometric analysis is necessary to model an osteotomy gap subjected to a maximum longitudinal strain of 100 percent. The large displacement, large strain conditions which were used in the in-vivo study result in complex, multiaxial strain fields in the gap. Restricting the maximum longitudinal strain to 10 percent allows use of a linear geometric formulation without compromising the numerical results. At this reduced strain level a linear material model can be used to examine the extent of material yielding within a homogeneous osteotomy gap. Severe local strain variations occurred both through the thickness of the gap and radially from the endosteal to periosteal gap surfaces. The bone/gap interface represented a critical plane of high distortional and volumetric change and principal strain magnitudes exceeded the maximum longitudinal strains.

Biomechanical Phenomena↗
PubMed1984

A contact-coupled finite element analysis of the natural adult hip.

A non-linear two-dimensional finite element model was used to study phenomena of stress redistribution in the natural adult hip resulting from parametric material property variations in the juxtarticular regions of the femoral head. Despite the geometrical simplifications employed, the intra-articular contact stresses (computed using the FEAP program) were found to be in reasonable qualitative agreement with previous in vitro data for the case of a normal hip. Generalized sclerotic changes in the subchondral plate, as reflected either in apparent modulus increases or in plate thickening, were found to have only minor effects on the computed contact stress distribution, although stress levels within the plate itself were markedly influenced. Localized subchondral plate sclerosis, by contrast, led to marked stress elevations in the cartilage immediately overlying the stiffened bone. Cartilage modulus increases caused increased load uptake for a given imposed deformation, but involved stress distribution increases which were very nearly linearly proportional to the increases in resultant load magnitude. Friction coefficient elevations had no noticeable effects on normal contact stress or upon overall load transmission, but involved complex, possibly slip-related, changes in intra-articular and cartilaginous shear stresses.

Cartilage, Articular↗