Search PubMed⌕ Search

Biomedical subjects

A M Adelstein

Publications and source records attributed to A M Adelstein.

52 records · Page 3Linked to original sources

Malignant disease in children whose mothers had chickenpox, mumps, or rubella in pregnancy.

To test the hypothesis that leukaemia may follow virus infection in pregnancy an analysis was made of deaths which occurred in a cohort of children born in 1951 and 1952 after pregnancies in which the mothers suffered virus infections-chickenpox or mumps at any stage of gestation or rubella in the first 18 weeks. All deaths which occurred between the children's second birthday and the end of 1971 were studied.Two deaths from leukaemia occurred among the children whose mothers suffered from chickenpox, a significant excess. There were no deaths from leukaemia among the other children, but the causes of the two deaths after maternal mumps-Ewing's tumour and Still's disease-are noted because of their rarity.

Acute Disease↗

Influenza and infant mortality.

Early neonatal mortality in England and Wales in the second quarter of 1970 after a major influenza epidemic was slightly but significantly higher than in the corresponding quarter of the previous year. An increase was also noted in the first quarter of 1970. Analysis of infant mortality and an index of influenza prevalence over the past quarter-century indicates that similar increases occurred in relation to four of the other five major influenza epidemics during the period, the exception being the "Asian 'flu" epidemic of the autumn of 1957. It is suggested that the increased mortality in 1970 was the consequence of an increase in the prematurity rate, but we have no evidence to indicate whether the effect is specifically due to the virus or is nonspecific in nature.

Birth Weight↗

Life-style in occupational cancer.

Data derived from the census report of 1970-1972 concerning occupational mortality in England and Wales have been analyzed in the light of particular hazards in work and life-style. For all cancer deaths there is a gradient rising from the highest social class to the lowest. Considering deaths among 25 occupational orders and the expected numbers for each order, it can be calculated that social class accounts for about 88% of the variation in cancer mortality.

Humans↗