Biomedical subjects

A Lueschow

Publications and source records attributed to A Lueschow.

3 recordsLinked to original sources

PubMed2002

Time-delayed decorrelation for the identification of cardiac artifact components in MEG data.

The time-delayed decorrelation (TDD) Independent Component Analysis (ICA) applied to continuous multichannel magnetoencephalographic (MEG) recordings is a straightforward calculation in the time domain: Its main ingredient is a calculation of the correlation between signals having different time shifts with respect to each other. The equivalent mathematical representation in the frequency domain and a simple simulation show that TDD exploits different complex frequency spectra of the sources. Applying ICA to 80-channel whole head MEG data obtained under visual stimulation we can assign five of the 80 source components to the cardiac artifact. Their complex spectra exhibit a randomly distributed phase showing that TDD is capable of isolating quasi-periodic signals even for the case of an unspecified phase.

Algorithms↗

PubMed2002

MEG-analysis using the Hilbert transform.

Event-related fields (ERFs) measured by magnetoencephalography (MEG) upon visual stimulation are analysed by Hilbert transformation. The Hilbert transform of real-valued measured ERF is an analytic complex signal, represented by phase and amplitude. The temporal behaviour of the derivative of the phase, i.e. the instantaneous frequency, allows to distinguish time intervals containing meaningful signal from noise. On the basis of both phase and amplitude, energies and latencies of single event ERFs can be determined.

Evoked Potentials, Visual↗

PubMedDate not supplied

Inferior temporal mechanisms for invariant object recognition.

The specific size and retinal location of an object are readily perceived, yet recognition of an object's identity is hardly affected by transformations of its size or location. To explore how such stimulus transformations are treated by known mechanisms for visual short-term memory in inferior temporal (IT) cortex, IT cells were recorded in monkeys performing a delayed matching-to-sample task. The stimuli were pictures of complex objects, and the monkeys ignored differences in size and retinal location when matching the test items to the sample held in memory. The sensory information communicated by cells was assessed in their responses to the sample stimuli, and mnemonic information was assessed in their responses to the test stimuli. In the sensory domain, the ordering of relative stimulus preferences for nearly all cells was invariant over changes in size or location; however, some cells nonetheless preferred stimuli of a given size or location. In the mnemonic domain, the responses of many cells were modulated according to whether the test stimulus matched the sample held in memory, and these memory effects were invariant over the relative sizes and locations of the stimuli. Thus, IT neuronal populations may mediate not only the recognition and memory of object identity, which are invariant over size and location, but also the perception of the transformations themselves.

Animals↗