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Biomedical subjects

A Ligabue

Publications and source records attributed to A Ligabue.

40 records · Page 3Linked to original sources
PubMedDate not supplied

Spectrophotometric phosphate assay in human seminal plasma. A technique for the determination of glycerol-3-phosphorylcholine secretion.

Glycerol-3-phosphorylcholine (GLY-3-PrC) has a role in determining the epididymal environment, but its function is not yet completely clear. This lack of knowledge might be partially due to the limitations of techniques currently employed in the GLY-3-PrC determination. In this paper we have studied and adjusted to human seminal plasma a spectrophotometric assay initially devised for bull and rabbit ejaculates. By means of column-chromatography and solvent extraction the specific interferences (up to 30%) present in human ejaculate, probably due to phosphatidylcholine, were avoided. The technique is precise, simple, cheap and shows GLY-3-PrC recovery higher than 90%.

Adult↗
PubMedDate not supplied

Cardiovascular and biochemical assessment in migraine patients submitted to tilt test.

Ten migraine patients underwent a tilt test both during migraine attack and headache-free interval, and the following parameters were assessed: plasma levels of norepinephrine (NE), and serum dopamine beta hydroxylase (D beta H), systolic and diastolic blood pressure and heart rate (SBP, DBP, HR). SBP during the tilt test showed a fall greater than 30 mmHg in 2 cases in the headache-free interval and in 4 cases during migraine attack. In migraine patients in headache-free interval, tilt test increased NE and D beta H as it did in the control group, while in migraine attack tilt test increased NE and D beta H less than in the control group. This impairment of the sympathetic nervous system during the migraine attack is discussed.

Adult↗
PubMedDate not supplied

Hypertension in end-stage renal failure: role of sympathetic nervous system, sodium balance and renal pressor system.

120 subjects, including 16 normal volunteers, 23 essential hypertensive and 81 uraemic patients (34 before the start of haemodialysis and 47 during maintenance haemodialysis) were studied in order to evaluate the interrelationship between mean arterial pressure (MAP) and total exchangeable sodium (NaE), plasma renin activity (PRA) and plasma catecholamines (PC). Significant positive correlations were noted between MAP and PRA and between MAP and PC in the total group of uraemic patients. In patients under conservative treatment MAP correlated significantly with NaE and PRA. Multiple regression analysis demonstrated that the combined effect of NaE and PRA accounted for 50 per cent of the levels of MAP. In patients undergoing chronic haemodialysis MAP lost any correlation with NaE. In these patients the presence of hypertension seemed to be related to the values of PRA and PC. PC increased after two hours of walking and hypertensive patients had higher increments than normotensive patients. These data might support an important role for the adrenergic system in the maintenance of hypertension in dialysis patients.

Adolescent↗