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Biomedical subjects

A Lifshitz Guinzberg

Publications and source records attributed to A Lifshitz Guinzberg.

18 recordsLinked to original sources
PubMed1992

Thyroid function and abdominal surgery. A longitudinal study.

Surgical trauma produces complex metabolic changes and may be an excellent model for studying the effects of an acute insult on the circulating thyroid hormone concentrations. Abnormalities in thyroid function tests in patients with nonthyroidal illness can be divided into a low T3 syndrome, low T3 and T4 syndrome in more severe cases and elevated T4 syndrome. In this study 30 patients undergoing elective or urgent abdominal surgery were longitudinally evaluated with pre- and postoperative thyroid function tests. Comparing with preoperative values, a significant reduction in total T3 serum values in the immediate postoperative period was seen (p < 0.005). The rest of the variables did not show significant statistical differences between the three periods. Over half of the patients undergoing urgent surgery had a low T3 syndrome, whereas only a sixth of the patients scheduled for elective surgery suffered from this syndrome. In the late postoperative period half the patients submitted to urgent surgery persisted with alterations in thyroid function tests, whereas most of the patients scheduled for elective surgery showed an improvement in their thyroid hormone level in the same period of time. Abnormalities in thyroid hormone metabolism were more frequent in patients admitted for urgent surgery, reflecting the severity of their illness and favoring the concept that these syndromes can be used as prognostic markers.

Abdomen↗
PubMedDate not supplied

[Thyroid function tests in healthy and ill elderly].

Thyroid function in the elderly has been a matter of discussion. The universe of the present study includes males and females 36 hospitalized with an average age of 72.97 +/- 8.70 years (group I) and 36 ambulatory asymptomatic elderly with 69.81 +/- 8.55 years of age (group II). Serum levels of T3, T4, T4L and TSH were measured in both groups. Mean values of T3 were significantly lower in the hospitalized patients than in the control group. The difference persisted on both, males and females, analyzed separately. Mean values of T4L were significantly lower in women of group II, while mean values of T3 were significantly lower in men of group I. The comparison of thyroid function tests in male and female showed that serum values of T3 and T4 were significantly lower in men of group I. By dividing results in age categories, serum levels of T4L in group II were significantly lower in the age group of 70 to 79 and 80 to 89. Thyroid function tests in asymptomatic ambulatory elderly tend to be normal, whereas the hospitalized patients showed a high proportion of alterations.

Aged↗
PubMedDate not supplied

[Protocol drafting of laparotomy in the diagnosis of the cause of fever of unknown origin].

Eighteen patients with fever of unknown origin in whom other diagnostic procedures had failed, underwent exploratory laparotomy with splenectomy, hepatic biopsies and biopsies of lymph nodes, muscle and bone, while bile, urine and intestinal content were cultured. In all patients, inspection and palpation of abdominal cavity doesn't give any diagnostic orientation. With histologic examination and cultures, precise diagnosis was made in 13 cases (72 per cent). Predominant diagnosis was Hodgkin's disease. One patient died with complications of surgery.

Biopsy↗
PubMedDate not supplied

[Rotor's syndrome. Report of a case].

Rotor's syndrome is a rare entity in our Country. We report here a case of this anomaly in a seventeen years old girl with jaundice from birth, normal biliary channels, elevated urinary coproporphyrins and retarded excretion of bromosulphalein with normal histology of the liver. The familiar study showed that the mother, but not the brothers, had a similar defect in excretion of bromosulphalein.

Adolescent↗
PubMedDate not supplied

[Early liver damage caused by alcohol].

Liver biopsy was taken from 20 patients with chronic and acute alcoholism. The patients had been hospitalized for diverse reasons, had no clinical manifestations of alcoholic hepatitis nor cirrhosis, but did have abnormal liver function tests. The most common abnormal test results were low serum albumin, polyclonal gamma-globulin elevation, and S G O T and Alk P rise. In all patients one or more types of hepatic lesiones were found: steatosis (15), polynuclear and mononuclear infiltrates (15), and portal (7), interstitial (13), or centriobular (8) fibrosis. Two patients had cirrhosis. None had hepatic cell necrosis. These findings justify a motivated search for liver damage in patients with alcoholism who have slight alterations in liver function tests, even in the absence of clinical manifestations of liver disease.

Adult↗
PubMedDate not supplied

[Uremia and hypothyroidism. Report of a case].

It was diagnosed hypothyroidism in a 53-year-old man with chronic renal failure, with blood urea of 306 mg/dl and serum creatinine of 14.9 mg/dl. At three months of triiodothyronine therapy, the patient became asymptomatic and blood urea and serum creatinine diminished to 49 and 1.1 mg/dl respectively. The possible mechanisms responsible of that reversible uremia of such unusual amount in this hypothyroid patient are discussed.

Electrocardiography↗
PubMedDate not supplied

[Alternatives against environmental pollution. The focus of the internist].

Potential pathogenesis from pollution depends on the kind of contaminant, its concentration, its duration in environment and on host's characteristics. Faced to the threat of medical consequences of pollution, it is necessary to be alert to recognize them, with an anticipated description. Two syndromes can be distinguished, one acute and the other chronic, that may be useful as reference for an eventual epidemiologic surveillance.

Acute Disease↗