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Biomedical subjects

A Lawrence

Publications and source records attributed to A Lawrence.

75 records · Page 5Linked to original sources

Is cranial CSF volume under hormonal influence? An MR study.

We used magnetic resonance to investigate the hypothesis that premenstrual neurological symptoms are due to cerebral oedema and brain swelling. Total cranial and lateral ventricular CSF volumes were measured midcycle and premenstrually in 20 women with a normal menstrual cycle, and similar measurements were made 2 weeks apart in 10 postmenopausal women and 10 men. Total cranial CSF volume increased premenstrually in 19 women. The mean premenstrual increase was by 11.5 ml. There was not a significant difference between those women who were taking an oral contraceptive and those who were not. The CSF volume did not change significantly on repeat measurement in men and postmenopausal women. The CSF changes observed reflect a reduction in brain volume and do not support cerebral swelling as the cause of premenstrual neurological symptoms.

Adult↗

Foot care education in renal patients with diabetes.

Foot complications are said to be the primary cause of hospitalization for patients with diabetes, resulting in enormous personal and financial costs. It is reported that end-stage renal disease (ESRD) diabetic patients with peripheral vascular disease have a much higher incidence of foot complications and increased risk for amputation. However, despite the serious financial burden caused by diabetic foot ulcers and their complications, the importance of diabetic foot care is still not fully recognised or supported. There is increasing evidence to suggest that education on foot care is essential for patients with diabetes. Studies have shown that simple techniques such as identifying those at risk of developing foot ulcers, educating patients about foot care that is tailored to meet the requirements of individual patient needs, educational background and learning ability can be of obvious benefit to people with diabetes and is cost-effective.

Diabetic Foot↗