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Biomedical subjects

A Laurens

Publications and source records attributed to A Laurens.

At least 37 records · Page 2Linked to original sources
PubMed1985

[Antimicrobial activity of some medicinal species from the Dakar markets].

After drawing up an inventory of Dakar markets popular medicinals plants, antimicrobial activity of 43 species have been screened. With the agar diffusion method, crude extracts of 24 species show an activity against Sarcina lutea or Escherichia coli. The antimicrobial spectrum of these extracts against 11 germs has been evaluated with the agar dilution method. 13 species show M.I.C. lower than 10 mg/ml against some germs. This preliminary study select some plants of potential interest for development of new antibacterial.

Anti-Bacterial Agents↗
PubMed1984

[Chromosome 11 abnormality in a case of acute monocytic leukemia (M5b)].

The authors report the case of a 25 year old man with a differentiated (M5 b) acute monocytic leukaemia resistant to polychemotherapy. The patient died four months after the onset of the disease. Cytogenic studies showed thickening of the long arm of chromosome 11, an abnormality considered until now to be specific for poorly differentiated (M5 a) acute monocytic leukaemias.

Adult↗
PubMed1979

[Bone localisation of Hodgkin's disease. A report on 13 cases (author's transl)].

The authors review 13 cases of bone localisation of Hodgkin's disease taken from 120 case-reports, and compare the findings with those reported in the published literature. The frequency of bone lesions in this series was 18%. Initial signs were clinical in one half of the cases and radiological or scintigraphic in the other half. Early diagnosis of bone lesions was more frequently made in this series than late discovery of bone locations; the lesions ware more frequently present in the spine, the pelvis, and the sternum; the usual appearance was osteolytic or mixed, lytic and condensed. Scintigraphy is a reliable early diagnostic procedure, as is medullary biopsy which has become essential for the investigation of extension of the lesions. An inflammatory syndrome is present in most cases. In this series, bone lesions usually were of haematogenic origin and were mainly of the scleronodular histological type. Definite recovery was obtained in more than half of the cases. In the other patients, the bone lesions coincided with a long disease course, were never the reason for great concern, and were never directly responsible for death in the 3 patients that died.

Adolescent↗
PubMed1979

[Malignant histiocytosis with bone involvement (author's transl)].

Malignant histiocytosis, an affection in which there is proliferation of morphologically atypical histiocytes, traditionally associates high fever, deterioration of the general condition, adenopathy, hepatosplenomegaly, and less frequently, cutaneous lesions. Clinical, radiological, and histological signs of bone involvement are rarely observed, which demonstrates the interest of the case reported of a pure medullary form with massive necrosis and successive bone localisations of the osteolytic type. The clinical picture was completed by the progressive development of adenopathy and hepatosplenomegaly. Multiple chemotherapy, according to the A.V.E.C. procedure, controlled the affection for three months before it became totally ineffective. Survival for twelve months after clinical onset demonstrates the extreme malignancy of the affection.

Adult↗