Biochemical and fine structure studies on the water-insoluble components of the calf lens.
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Biomedical subjects
Publications and source records attributed to A Lasser.
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In a series of 1,002 cases of primary colorectal adenocarcinomas diagnosed during a ten-year period there were 62 (6.2%) patients who had two or more primary colorectal adenocarcinomas. Most of the tumors were more than 5 cm away from each other: 27 carcinomas were separated by 6-10 cm, 16 were separated by 11-20 cm, and 12 were separated by more than 20 cm. It is concluded that the incidence of synchronous carcinomas of the colon is sufficiently high to warrant a search by both surgeon and endoscopist for additional tumors some distance from the initial lesion.
Five cases of prostatic carcinoma invading the rectum were found on reviewing 161 prostatic carcinomas over a five-year period. A summary of the clinical and laboratory findings of these cases is given. A review of previous reports in the literature and discussion of the modality of presentation and methods of diagnosis of this entity are presented. The importance of differentiating a primary rectal carcinoma from a prostatic carcinoma involving the rectum is emphasized.
Two cases of stercoraceous perforation of the cecum with adjacent mass formation simulating a neoplasm are described. The predisposing factors for the formation of fecalomas and the mechanisms of perforation are discussed and a review of the literature on this subject is presented. There were no demonstrable predisposing colonic lesions to account for the fecaloma formation in these casesmboth patients recovered completely after surgical treatment of the lesions.
Two cases of herpes simplex virus esophagitis diagnosed in vivo by cytologic examination and biopsy of the lesion are reported. The importance of and the criteria for the diagnosis of herpes esophagitis in vivo are discussed. An awareness by the clinician and pathologist of this lesion would probably result in a more frequent diagnosis of herpes esophagitis.
A case of renal-cell carcinoma metastatic to the thyroid eight years after the removal of the primary tumor is presented, with the aspiration cytologic and histologic findings described. This unusual presentation and the incidence and behavior of renal-cell carcinomas and tumors metastatic to the thyroid are discussed.