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Biomedical subjects

A Lacassagne

Publications and source records attributed to A Lacassagne.

At least 37 records · Page 2Linked to original sources

5-oxo-5H-benzo[e]indole, a new type of highly sarcomagenic lactone.

The title compound, which belongs to a new synthetic group of polycyclic lactones derived from isocoumarin, exhibits a remarkably high degree of carcinogenicity in situ when injected in mice. Cancer-inducing activity has also been found in similar isocoumarins, a family known to include many naturally occurring substances.

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