Biomedical subjects

A L Sisk

Publications and source records attributed to A L Sisk.

43 records · Page 3Linked to original sources

PubMed1984

Evaluation of etidocaine hydrochloride for local anesthesia and postoperative pain control in oral surgery.

Etidocaine hydrochloride, an amide-type local anesthetic with prolonged duration of action, was evaluated and compared with a standard local anesthetic, lidocaine, to determine its efficacy as a local anesthetic and its effect on postoperative pain following removal of impacted third molars. The findings indicate that 1.5% etidocaine hydrochloride with 1:200,000 epinephrine, in comparison with 2% lidocaine hydrochloride with 1:100,000 epinephrine, suppresses the magnitude of postoperative pain, and results in anesthesia comparable with that obtained by lidocaine, but results in greater blood loss during surgery.

Acetanilides↗

PubMed1984

A simple means of maintaining light handle sterility.

The maintenance of sterility of the light handle in an economical and effective manner can be difficult. Heavy-duty aluminum foil is suggested as a simple and inexpensive material to be used to maintain such sterility in the clinical practice of oral and maxillofacial surgery.

Lighting↗

PubMedDate not supplied

Evaluation of the Gow-Gates mandibular block for oral surgery.

The Gow-Gates mandibular block technique for administration of local anesthesia was compared to conventional nerve block techniques in patients undergoing the removal of impacted third molars, using a within-subject experimental design. Both techniques resulted in acceptable quality of anesthesia. Success rate of the Gow-Gates technique was significantly greater than with conventional techniques. Limitations of the Gow-Gates technique were slower onset of anesthesia, variable buccal nerve anesthesia, and increased intraoperative bleeding.

Adolescent↗

PubMedDate not supplied

Reduction of venous complications of intravenous diazepam.

Nonsteroidal anti-inflammatory agents (NSAIAs), administered preoperatively and for three days postoperatively, were evaluated for reduction in the occurrence of venous complications following conscious sedation with intravenous diazepam. Patients receiving NSAIAs had significant reduction in overall incidence of postoperative venous complications when compared to a control group receiving postoperative narcotic analgesics.

Anesthesia, Dental↗

PubMedDate not supplied

Surgical treatment of chronic orofacial pain.

There are many conditions in which chronic orofacial pain is a major diagnostic and therapeutic problem. It is generally accepted that surgical treatment for these chronic pain problems should be resorted to only when more conservative treatments have been ineffective. Literature concerning selected orofacial pain problems is reviewed and the indications for surgical management are discussed.

Arthritis↗

PubMedDate not supplied

A comparative investigation in dogs: 2-year morphometric results of the dental implant--bone interface.

One hundred twenty titanium and ceramic root-form and titanium blade implants were placed into 30 dog mandibles. Twenty-four implants in six control dogs (in situ for 5 months) did not receive prostheses. Ninety-six implants in 24 dogs supported prostheses for 6, 12, 18, or 24 months. Computerized morphometry data presented the percent of the implant surface apposed directly by bone. A three-way factorial analysis of variance was used to assess significance. Individual implant means ranged from 0% (mobile implant) to 71% bone adaptation. From these data, two-stage titanium root-form implants were shown to be apposed by more bone than the other five systems, and overall, titanium implant systems were apposed by more bone than ceramic systems. Between 41% and 50% of the surface of integrated ceramic implants were apposed by bone, whereas between 50% and 65% of the surfaces of titanium implants were apposed by bone. Also, two-stage surgery for blade implants appears important for implant success. Furthermore, the use of Nomarski differential illumination appears to be useful for examining the quality of interfacial bone to correlate with the amount of bone quantified by morphometric protocols.

Analysis of Variance↗

PubMedDate not supplied

Composite morphology of the bone and associated support-tissue interfaces to osseointegrated dental implants: TEM and HVEM analyses.

Correlated transmission electron and high-voltage electron microscopic analyses examined the undecalcified bone and associated support tissues of 60 endosseous titanium blade and titanium and ceramic root-form implants in dogs. The implants supported fixed partial dentures for up to 2 years. Data obtained from this investigation suggest that a range of tissues, both mineralized and unmineralized, support osseointegrated dental implants. This study examined the tissues apposing not just isolated aspects of the implant surface, but the entire length of the implant, and found that mineralized and unmineralized tissues existed concurrently. Much of the implant surface was apposed by mandibular bone, and both root-form and blade implants osseointegrated. The densely mineralized collagen fibril matrix was often separated from the implant by only a 20-nm to 50-nm electron-dense, ruthenium-positive deposit. High-voltage electron microscope stereology demonstrated that cellular processes extended directly to the implant from underlying osteocytes. In the same implants, areas containing an unmineralized collagen matrix interposed between the bone and implant surface were observed. In this region osteoblasts interacted with this matrix, and Howship's lacunae, containing vascular elements and osteoclasts, were also observed. The remodeling activities appear to be a homeostasis of catabolic activity (osteoclasts) and metabolic activity (osteoblasts). The apex of the implant was often apposed by a fibrofatty stroma. The support tissue response appears to be the result of the interrelations of osteoblasts, osteocytes, and osteoclasts in association with vascular elements. Therefore, the support tissue response to osseointegrated implants is a dynamic activity that involves the healthy interaction of these cells and tissues along the entire length of the implant.

Adipose Tissue↗