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Biomedical subjects

A L Jackson

Publications and source records attributed to A L Jackson.

41 records · Page 3Linked to original sources
PubMed1965

Humoral and cellular aspects of the immune response to the somatic antigen of Salmonella enteritidis.

A study was made of the cellular and humoral aspects of the immune response of the rabbit to the somatic polysaccharide of Salmonella enteritidis. The response to a single intravenous injection was characterized by the appearance of elevated titers of bactericidal antibody between 2 and 3 days later. The maximum titer was dose-dependent and occurred between 5 and 7 days, thereafter declining rapidly during the first month. The significant stabilized levels which then persisted for at least 1 year were also dose-dependent. Most of the antibody produced (>99 per cent) was associated with the macroglobulin fraction of serum. Plaque-forming cells (PFC) elaborating antibody specific for this somatic antigen were detected and enumerated by the technique of localized hemolysis in gel employing polysaccharide-coated sheep erythrocytes. Significant numbers of PFC were encountered in the spleen as early as 14 to 18 hours after a single intravenous injection of antigen; after 36 hours the number of PFC rose rapidly and culminated in a maximum population at 5 days, followed by a rapid decline and plateau similar to that for circulating antibody. The spleen was the principal organ involved in the systemic response, but other lymphoid tissues including bone marrow, peripheral blood leucocytes, and thymus contributed significantly. After an interval of 3 months the effect on humoral antibody titers of a second injection of antigen was dependent on the amount of polysaccharide administered; markedly greater titers were now obtained with 0.02 to 0.002 microg, whereas 0.2 to 20 microg resulted in a duplication of the initial humoral response. The cellular response to a second dose of 5 microg was accelerated; larger numbers of PFC appeared more rapidly, attained a maximum population by day 3, and exceeded the primary response by a factor of two. This acceleration in the attainment of maximum numbers of PFC and the increased bactericidal antibody titers following a second injection of limiting amounts of antigen suggest that these somatic polysaccharides may in fact evoke a "secondary" type of response in the rabbit.

Animals↗
PubMedDate not supplied

Relative satisfaction with nursing care of patients with ostomies.

Nurses and patients engage in an interactive process that is both supportive and educational. The ability of the nurse to communicate with the patient in a manner that the patient perceives as accepting will lead to transaction, goal attainment, effective nursing care, and satisfaction. This study was undertaken to examine the relationship between nurses' perceptions of patients with ostomies and those patients' satisfaction with nursing care. Data were also collected on nurses' confidence in caring for patients with ostomies, the length of time with the patient, and previous experience in caring for patients with new ostomies. Twelve patients with new ostomies and the registered nurses who cared for them on postoperative units at a regional medical center and a community hospital were identified. Reed's 1989 adaptation of Yuker, Block, and Young's 1972 Attitudes Toward Disabled Persons scale was used to obtain the nurse's perceptions of patients with ostomies. The LaMonica-Oberst Patient Satisfaction Scale was used to obtain the ostomy patients' satisfaction with nursing care. No statistically significant relationship was identified between nurses perceptions of patients with ostomies and these patients' satisfaction with care. However, the data suggest that there may be a relationship between higher patient satisfaction scores and three factors: the nurse's confidence in caring for patients with ostomies, the length of the nurse-patient relationship, and the employment of a certified ET nurse in the hospital in which the patient receives nursing care.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMedDate not supplied

Operation Sunday School--educating caring hearts to be healthy hearts.

This project seeks to improve traditional hypertension screening of the black population by developing a community oriented approach that can increase knowledge and involve a new target group--black children--in preventive techniques. To help achieve the educational goals, an anti-hypertensive picture book for black children has been designed. The picture book will be distributed through church Sunday School classes. Several black churches in Chicago that were willing to host hypertension screenings for their congregations were identified; the picture books will be distributed through their Sunday School classes. Medical students, physicians, and members of the Black Nurses Association have been recruited to work collaboratively to introduce the picture book-manual, to instruct children on how to measure blood pressure, and to assist in the initial hypertension screenings at the churches. Funding is needed to print the manual and purchase sphygmomanometer sets for training. With the manual, equipment, and proper instruction of the children, each church will have the manpower to screen its at-risk population as often as possible. Educating black children about hypertension and its detection increases their awareness and provides them with the knowledge to screen adults. The success of this community support system is the exchange of knowledge between children and adults and the constant followup and preventive intervention supplied through a dominant community organization, the black church.

Black or African American↗