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Biomedical subjects

A L Ball

Publications and source records attributed to A L Ball.

3 recordsLinked to original sources

Effect of a mixture of seven pharmaceuticals on Hyalella azteca over multiple generations.

A mixture of seven common pharmaceutical agents (acetaminophen, diclofenac, gemfibrozil, ibuprofen, naproxen, salicylic acid, and triclosan) was tested for its effects on the freshwater amphipod Hyalella azteca over three generations. The target concentration of each chemical (100ngl(-1)) was representative of the upper range observed for these substances in Canadian fresh waters, except in the immediate vicinity of effluent discharges. No statistically significant effects were observed on survival, mating, body size or reproduction. The sex ratio changed slightly to 17% more males. The seven pharmaceuticals tested do not appear to be substances of major concern for Hyalella in most Canadian fresh waters, but significant impacts might be observed in areas closer to effluent discharges.

Amphipoda↗

Introduction.

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Journal Article↗

HIV prevention among injecting drug users: responses in developing and transitional countries.

OBJECTIVE: Human immunodeficiency virus (HIV) infection associated with injecting drug use has been reported in at least 98 countries and territories worldwide. There is evidence that new epidemics are emerging in different regions, including Eastern Europe, Latin American, and the eastern Mediterranean. The authors provide a global overview of the situation of HIV infection associated with injecting drug use and responses that have been implemented in various developing and transitional countries. METHODS: Although there has been extensive documentation of the extent and nature of of HIV infection associated with injecting drug use in many developed countries and the various interventions implemented in those countries, there is very limited information on the situation in developing and transitional countries. This chapter brings together information from a broad range of sources, including published literature; "gray" or "fugitive" literature; data collected by the World Health Organization (WHO), the Joint United Nations Programme on HIV/AIDS (UNAIDS) and the United Nations International Drug Control Programme (UNDCP); personal communications; and direct observation by the authors. The authors have traveled extensively to a wide range of developing and transitional countries and have accessed information not readily available to the international research community. RESULTS: A wide range of HIV prevention strategies targeting injecting drug users (IDUs) has been implemented in developing countries and countries in transition. Interventions include opioid substitution pharmacotherapy, needle syringe exchange and distribution, condom and bleach distribution, outreach to IDUs, peer education programs, and social network interventions. In some communities, completely new models of intervention and service delivery have developed in response to specific local needs and limitations. CONCLUSIONS: Although empirical data may currently be lacking to demonstrate the effectiveness of may HIV prevention programs targeting IDUs in developing and transitional countries, there is evidence that innovative HIV prevention initiatives are being implemented and sustained in a wide range of sociocultural settings.

Developing Countries↗