[Histography of intracranial pressure. Practical clinical application].
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Biomedical subjects
Publications and source records attributed to A Kunicki.
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Symptoms and therapeutic results are reported in 21 cases of the sphenoidal ridge meningiomas. These meningiomas are usually not recognized in an early stage of typical of intracranial tumours. Headaches as an early symptoms were the complaint in only 10 cases. In the stage of clinical manifestations 9 patients had no visual disturbances, in 4 cases the eye fundus was not changed, in 13 there were no visual field defects. Unilateral exophthalmos was present in 5 cases, radiological changes in 13. The first five patients operated upon under local anaesthesia were lost, but out of the remaining 16 patients operated upon under general anaesthesia only 1 died of septicaemia three weeks after the operation. A considerable facilitation of the operation was the sitting position of the patients which make possible a good insight into the operation field (Fig. 1). At the time of collecting data about the fates of the patients 10 lived without help, six of them returned to their previous occupations, and 4 other ones were partly disabled because of poor visual acuity. Two patients required continuous care because of frequent epileptic seizures. One patient had recurrence after 3 years and was treated surgically again with success.
In patients with expanding intracranial lesion syndrome osmotic pressure of the serum was measured during administration of furosemide or 20% mannitol solution. Mannitol was administered by two methods: a) a dose of 1.5 g/kg during 3--4 hours, b) a dose of 1 g/kg for about 20 min. When mannitol was administered slowly the osmotic pressure of the serum at the end of infusion was 11--15% above the initial one and returned to the initial level 30--60 min. after the end of infusion. With rapid infusion the peak rise of pressure was observed after 30 min. usually after the end of infusion, and after one hour the pressure returned to values approaching the initial ones. Furosemide in a dose of 40 mg intramuscularly or intravenously caused slight changes of osmotic pressure reaching 13 mOsm/l.