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Biomedical subjects

A Kuhrmeier

Publications and source records attributed to A Kuhrmeier.

5 recordsLinked to original sources

[100 consecutive cases of surgical esophagus-cardia carcinoma].

100 esophagectomies were performed at the Waid Hospital in Zürich between 1981-1988. 55 patients underwent blunt esophagectomy without thoracotomy, 34 abdomino-thoracic resection with intrathoracic anastomosis, and 11 abdomino-thoracic resection with lymphadenectomy and cervical anastomosis. In 80% the tumor had spread through the esophageal wall or there were already regional lymph node metastases. Adenocarcinoma was found in 2/3 of the patients and epidermoid carcinoma in 1/3. 30-day mortality was 5%. The actuarial 5-year survival rate is 14%. Average hospital stay was 30 days. Blunt esophagectomy was mainly performed in older patients with tumor localization in the lower third. Abdomino-thoracic resection with cervical anastomosis was preferred for younger patients with tumor localization in the middle third. Surgical resection is the only curative therapy in esophageal cancer, but due to the often advanced tumor stage it is often only of palliative character.

Adenocarcinoma

[Mesenteric lipodystrophy].

Mesenterial lipodystrophy is characterized macroscopically by a light yellow nodular or diffuse thickening of the mesenterium. Microscopically, infiltration of the mesenteric adipose tissue with lipid containing macrophages predominates. Mesenterial lipodystrophy is a rather common finding in autopsies. To obtain more information about the frequency and the nature of these alterations, the mesenterium of all adult autopsies during a period of 6 months was investigated. 9 out of 712 autopsies (1.26%) showed mesenterial lipodystrophy. In these cases as well, the typical macroscopic findings were nodular or diffuse mesenterial thickening partly discoloured to light yellow or orange-brown. Microscopically, infiltration of the adipose tissue with foamy cells predominated. Monocytic cells, and occasionally fibrosis, were also found. Retrospective study of the case histories gave no clinical hint of the underlying disease, except for unspecific abdominal discomfort in one case. In the literature the clinical finding is described as a rather soft abdominal tumourous mass. This disorder seems to follow a predominantly favourable course, even without therapy. Even today the etiology and pathogenesis of mesenterial lipodystrophy is unclear. Depending on the histological findings, very different terms have been applied to similar mesenterial processes.

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