The aim of the study is the comparison of the basic features of the isolated amphibians lungs (R. temporaria with B. marinus and R. catesbeiana) and the evaluation of this preparation as a model of the chloride transport. Measurements of the bioelectric properties of the isolated lungs were performed according to Ussing. Chloride unidirectional fluxes were measured in chambers described by Helman according to Gatzy. The spontaneous potential difference of the lung was of the range of milivots. The short circuit current was of the order of microampers. The net flux of chloride was directed to the mucosal side. The current-voltage relationship was linear in the range of the +/- 30 microampers. The measured functions were stable during the study only when ambient temperature was about 10 degrees C.

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Spirometric, gasometric and electrocardiographic studies in patients with extreme obesity prepared for surgical treatment.

Spirometric, gasometric and electrocardiogarphic studies were carried out in 17 patients at rest, who were treated surgically for extreme obesity (overweight from 52 to 175 per cent in relation to the normal weight). The measurements were made before operation. It was found that the mean spirometric values were within the range of acceptable deviations from the normal value. The residual volume showed a tendency towards decreasing, especially in young patients. The values of dynamic parameters indicated a tendency towards ventilatory changes of a restrictive type in both groups. Minute ventilation at rest increased proportionally to obesity. Decreased values of respiratory equivalent indicated a good economy of respiration in obese persons when at rest. The mean gasometric values in capillary blood at rest were also within the acceptable range of abnormalities. Electrocardiographic tracings taken at rest showed considerable changes in the group of more obese persons.

Adult↗