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Biomedical subjects

A Krauss

Publications and source records attributed to A Krauss.

At least 19 recordsLinked to original sources

[Therapy trends in the prevention of radiation-induced diarrhea after pelvic and abdominal irradiation. Results of a tricenter study].

PURPOSE: Radiotherapy induced diarrhea and convulsive pain are severe side-effects of irradiation of the pelvis and the abdomen leading often to an interruption of the treatment. Up to now these side-effects were only treated symptomatically, prophylactic therapies are not known. PATIENTS AND METHODS: During the years 1992 and 1993 174 patients who obtained radiotherapy in the pelvis or the abdomen because of different malignancies were observed referring to the diarrhea-prophylactic effect of Smectite (= Skilpin). 80 patients received Smectite at the beginning of radiotherapy, 94 patients of the control group were treated with motility modifying drugs when diarrhea appeared. The following parameters were compared: Frequency, consistence and incontinence of stool, tenesmus and the onset of diarrhea. RESULTS: 67.0% (n = 63) of the patients in the control group developed diarrhea, whereas in the pretreated Smectite-group only 37.5% of the cases (n = 30) developed diarrhea. The first appearance of diarrhea was at day 17 in the pretreated group and averagely at day 11 in the control group. 44% of the patients in the control group suffered from tenesmus versus 25% in the Smectite-group. CONCLUSION: In comparison to the symptomatic treatment of radiation enteritis the prophylactic application of Smectite is able to reduce the diarrhea from the beginning of radiotherapy or at least to reduce the pathological frequency of stool and therefore to increase the quality of life.

Abdomen

Developing the gastroenterology certification examination.

This paper describes a typical procedure for the development of credentialing examinations. Specifically, the paper provides the developmental history of the Certification Examination for Gastroenterology Nurses and Associates. In the course of the paper, a four-step approach to examination development is outlined. The steps include role delineation, item writing, examination construction and passing score determination. All phases of the examination development process are viewed in the light of their contribution to the public protection responsibility of the Certifying Board of Gastroenterology Nurses and Associates.

Certification

[Cough associated with captopril and enalapril].

Persistent dry cough is not a known adverse reaction of captopril and enalapril. We present 5 patients with persistent dry cough severe enough to warrant withdrawal of the drug, which resulted in rapid and complete recovery. Challenge with the drugs induced recurrence of cough. The pathogenesis of the reaction is unknown, but possible mediators include bradykinin and prostaglandins.

Aged

Treatment of hypertension in mild asthmatic patients with atenolol.

Fourteen patients with uncomplicated essential hypertension and mild asthma were treated with Atenolol 50-125 mg/day for up to 8 months. Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), rate pressure index (RPI), stress testing time (STT) and peak expiratory flow rate (PEFR) were measured before, during and after stress testing (ST) before and during treatment. Atenolol significantly lowered HR, SBP, DBP and RPI. It prolonged STT and had no effect on PEFR. Furthermore, Atenolol did not worsen the patient's asthma except for one patient. The drug did not interfere with the bronchodilatation effect of salbutamol. Atenolol can be used cautiously to treat hypertension in asthmatic patients under certain conditions.

Adult

Infants of mothers treated with ethanol for premature labor.

Presented is a retrospective study of the newborn infants of mothers who were treated with ethanol in order to arrest premature labor, in comparison with matched control infants. In regard to neonatal mortality, there was no statistical difference between the study and the control infants. However, infants born within 12 hours after administration of ethanol had a significantly lower 1-minute Apgar score and a higher incidence of respiratory distress syndrome. This indicates that treatment with ethanol should be discontinued as soon as it becomes evident that labor cannot be arrested.

Apgar Score

[Pilot study into habitual abortion (author's transl)].

Endocrinic functional disorders obviously are more relevant than other factors to the aetiology of habitual abortion. Delayed menarche combined with menstrual disorders played a major role among the probands examined by the authors. Diagnosis of habitual abortion should be extended, with the view to elucidating other known causes of abortion for their importance to the situation under review. It is not recommended to start diagnosis as late as after the third abortion. A two-phase programme should rather be applied to women who wish to have children, as early as after two consecutive abortions.

Abortion, Habitual

[Developmental trends in obstetrics at the Leipzig University-Gynecological Hospital since the existence of the German Democratic Republic].

An analysis of development in the obstetrics allows following comments: Peripartal and perinatal mortality shows a significant positive development. Maternal mortality has become very rare. The high percentage of approximately 10% of premature birth has a bad influence on the perinatal mortality. The intranatal mortality compared to ante- and post-natal could be sunk to a great extent. The eclampsia is observed very rarely. The reasons for the good results are to be seen not only in widening of indications of obstetrical operations but also in improvement of solicitude, prophylactical, diagnostical and conservative therapeutic measures.

Female