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Biomedical subjects

A Keszler

Publications and source records attributed to A Keszler.

17 recordsLinked to original sources

Oral pathology in children. Frequency, distribution and clinical significance.

A statistical study of 1289 biopsies of children 0-15 years old, received at the Pathology Department, Dental Faculty, Buenos Aires University is presented. This number, represents 6.8% of the 18,966 biopsies received from 1960 to 1985. The histologic diagnosis were grouped into the following categories: 1) cysts, 2) tumour-like lesions, 3) inflammatory lesions, 4) neoplasms, 5) neck and head non-oral lesions, 6) dental anomalies and pulp diseases, 7) unclassified diagnosis. Cysts were the most frequent lesion (25.4%). 75% were localized in the jaws and 25% in soft tissue. Bone tumour-like lesions (20.1%) were less frequent than the soft tissue tumour-like lesions (79.9%). Inflammatory lesions and neoplasms in children, account for 15.7% and 10.2% of the lesions respectively. Eighty four percent of the neoplasms were benign and 16% were malignant. Odontogenic tumours constituted 49.6% of all the neoplasms studied. These results indicate the need to be constantly aware of the possible presence of these clinical and radiographic lesions to allow for early diagnosis and adequate treatment.

Adolescent

Comparative study of keratocysts, associated and non-associated with nevoid basal cell carcinoma syndrome.

Keratocysts of the solitary type were histologically and histometrically compared with those associated with the nevoid basal cell carcinoma syndrome (NBS). It was observed that parakeratinization, intramural epithelial remnants and satellite cysts were a more frequent finding among NBS keratocysts than among solitary keratocysts. Conversely, it was also found that the total nuclear density was greater in non-associated cysts and that the total number of nuclei, the number of basal nuclei and the epithelial height values were also higher in solitary keratocysts. NBS-keratocysts and solitary keratocysts are considered to be two morphologically distinct populations of the same entity.

Basal Cell Nevus Syndrome

Ameloblastoma in childhood.

Clinical, radiologic, and histologic studies were performed in eight cases of ameloblastoma in patients younger than 16 years of age. The mean age of the patients was 10.8 years, equal numbers of males and females were affected, and the most common location was the lower molar and ramus areas. Radiologically, a monocystic osteolytic image was observed in all cases. Histologically, two forms of growth were observed: an intramural, infiltrating, plexiform or follicular type, and a polypoid type, prolapsing toward the lumen of a cystic cavity. The ameloblastomas recurred in three cases a year after surgery.

Adolescent

The formocresol technique in young permanent teeth. A histopathologic study.

Twenty-six extractions were performed at random among seventy-six young, permanent teeth, treated by the formocresol technique, between 5 and 20 months after treatment: twenty-one with penetrating caries (nine vital and twelve nonvital) and five healthy. As a control group, thirteen permanent teeth with penetrating caries were removed: seven vital and six nonvital. The histopathologic analysis compared pretreatment and posttreatment radiographic examinations. In the control cases, there was almost always inflammation and/or necrosis in the entire root canal. In the experimental cases, fibrosis and osteodentin predominated in the apical third, diminishing gradually near the cervical third. Inflammation and necrosis, very low in the apical third, increased similarly near the cervical third. This response seems to be a stage in a process of evolution in biologic scar healing. The complete cure must require a greater lapse of time than that of this experiment--around 10 to 12 months.

Adolescent

Histometric study of leukoplakia, lichen planus and carcinoma in situ of oral mucosa.

Leukoplakia, lichen planus and carcinoma in situ of human oral mucosa were analysed histometrically by light microscopy. Leukoplakia lesions showed a greater total nuclear density than lichen planus lesions. They had a similar basal nuclear density to carcinomas in situ. The total and basal nuclear areas were notably greater in carcinomas in situ, indicating the presence of larger nuclei in comparison to those of other lesions. We believe it to be possible to make a differential diagnosis based on numerical variables.

Carcinoma in Situ

[Histomorphometry of dentigerous cysts in children, associated or not with formocresol].

Literature reports appeared in the last years suggested that some type of dentigerous cyst (DC) in children would initiate by teh action of other factors than developmental and at different stages of dental sac growth. Periodontitis and pulp therapy with formocresol (FC) have been suggested as aeteological factors, both promoting DC in children by irritation of the underlaying dental sacs of premolar. The purpose of this study is to analyse the pathological changes in DC of patients aged 0 to 15 years, and to compare the findings according to the anatomical site of DC and the existence of previous FC therapy. Morphological changes observed in the epithelium and the connective wall did not show clear differences between both groups of DC. The histometric measurements of epithelial changes did not show significant statistical differences of various parameters in the DC walls. These facts would not support the hypotesis of DC initiation from FC effects.

Adolescent

[Frequency and distribution of oral lesions in elderly patients].

In this study the relative frequency of oral lesions was evaluated in a group of 526 patients, 55 years old or elder. Clinical and pathological data were obtained from 244 patients who attended to a clinic of Medical and Social Assistance Program (PAMI) ad from 282 cases registered in the files of the Surgical Pathology Laboratory F.O.U.B.A. (LAP) since 1984 to 1986. The mean age of the groups was 63 years old. The most frequency lesions were the pseudotumors (44.6%) in LAP and (17.2%) in PAMI; premalignant lesions were (20.5%) in LAP, while in PAMI (2.4%). The cysts in LAP found (15.6%) in PAMI were (2.4%). The groups of PAMI showed (90%) of Candidiasis. Traumatic ulcer (30.7%) and afthae (28.8%). In LAP were (4.6%) the traumatic ulcer. The malignant tumors the most frequency was carcinoma espinocelular (8.16%) LAP and (6.56%) PAMI. It was remarkable that stomatodine as represented in PAMI (72.2%) and Candidiasis were (90%). Candidiasis were 90% of the specific inflammations. Results suggest that oral mobility in elderly patients correlates with the findings in this type of social assisted groups. The figures of the importance of methodical collaboration of Stomatologists and Oral Pathologists for differential diagnosis.

Aged

[Oral manifestations in AIDS or HIV infection. Bibliographic update].

AIDS is a systemic infection that in many steps of its evolution presents various oral lesions and clinical conditions. This fact raises a problem for the dentist who are working on heterogeneous populations of healthy and infected people as well as on AIDS patients: to receive a continuous update about the disease. Apart from the risks of exposure inherent to his personal relation with HIV-infected or AIDS patients, the dentist is one of the health careworkers who must and ought recognize the oral signs of the disease when they appear in the mouth. For this reason this paper describes recent data on oral findings in AIDS: fungal, viral and bacterial infections, neoplasms and other manifestations of unknown or rare etiology. The most precocious clinical or pathological characteristics of these oral diseases suggesting HIV-infection or its results, are also stressed when described. Some doubts are possessed here about the meaning of outstanding oral AIDS lesions as "hairy leukoplakia". On the other way diagnostic methods which can help to recognize this lesion are also commented.

Acquired Immunodeficiency Syndrome