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A Kemona

Publications and source records attributed to A Kemona.

90 records · Page 5Linked to original sources
PubMedDate not supplied

Papillary Hürthle cell tumor of thyroid: report of a case with a cytomorphologic approach to diagnosis.

BACKGROUND: Hürthle cells are founded often in fine needle aspirates of the thyroid from nonneoplastic and neoplastic lesions. Papillary Hürthle cell tumors of the thyroid are composed of oxyphilic cells with a prominent papillary component. Papillary Hürthle cell carcinoma is a relatively uncommon type of thyroid carcinoma. CASE: A 42-year-old man had two asymptomatic nodules (2.5 and 3.5 cm) in the left lobe and one (2.5 cm) in the right lobe of the thyroid. Fine needle aspiration biopsy of the tumor in the left lobe showed large cells in monolayers and papillary clusters with moderate to abundant eosinophilic, granular cytoplasm with sharp borders, a granular nuclear enlargement with pleomorphism and single nucleoli. Histologic examination showed capsular invasion and infiltration of vessels. CONCLUSION: The cytologic appearance of papillary Hürthle cell carcinoma is not specific but can be suspected on fine needle aspiration.

Adenoma, Oxyphilic↗
PubMedDate not supplied

Morphological changes in mitochondria and lysosomes of hepatocytes in acute intoxication with 2,4-dichlorophenoxyacetic acid (2,4-D).

The hepatotoxic effect of 2,4-dichlorophenoxyacetic acid (2,4-D) was investigated. Ultrastructural changes were evaluated under a transmission electron microscope. Certain histoenzymatic reactions were examined (to acid phosphatase according to Gomori (AP) and to succinic dehydrogenase (SD) according to Nachlas) in parenchymal cells of the rat liver in acute intoxication induced by this herbicide. The experiment used 60 male Wistar rats divided into two groups: I-control--18 animals and II--42 animals which received chemically pure 2,4-D acid by gastric gavage in a dose of 200 mg/kg b.w. The animals were sacrificed after 12, 24, 48 hours and 4, 10 and 30 days of the experiment. The results indicate that the administration of 2,4-D acid to rats in a dose inducing acute intoxication leads to histoenzymatic and ultrastructural changes in the liver, which suggest nonspecific reversible adaptive-type damage to parenchymal cells. The changes observed indicate disorders in energetic processes in hepatocytes and are morphological exponents of intense detoxicative processes.

2,4-Dichlorophenoxyacetic Acid↗
PubMedDate not supplied

Evaluation of selected cytokines and mononuclear cell infiltration in gastric mucosa of children with food allergy.

The authors performed simultaneous evaluation of histological changes in gastric and duodenal mucosa, phenotypic evaluation of mononuclear cells infiltration and the levels of selected cytokines of gastric mucosa in children with diagnosed food allergy. It was determined that IL-4, IL-5, IL-10 and TNF-alpha were produced locally within alimentary tract mucosa; they may play pathogenic role in food hypersensitivity in children. Increase in the number of T lymphocytes (CD3+, CD8+) and B lymphocytes (CD20+) as well as mastocytes with positive reaction to Mast Cell Tryptase-Mastocyte antibody was also observed in gastric and duodenal mucosa of these patients.

Adolescent↗
PubMedDate not supplied

Omeprazole therapy and salivary flow rate in duodenal ulcer patients.

BACKGROUND: Previous reports have shown that in some reflux-oesophagitis patients omeprazole therapy alters salivary secretion. The aim of the study was to examine this effect in duodenal ulcer patients. MATERIAL AND METHODS: Thirty nine Helicobacter pylori positive subjects of both sexes, predominantly men, were recruited for the study. They were taking for two weeks only omeprazole (n = 17), or omeprazole in combination with either amoxycillin or amoxycillin and tinidazole (n = 22). Salivary secretion was assessed before and at the end of the treatment, both in basal conditions and during a gastric secretory test. Gastric secretion was monitored concurrently with salivary flow rate. Additionally gastritis score and serum gastrin levels were assessed. RESULTS: Basal salivary secretions remained unchanged in patients on omeprazole monotherapy, but decreased in five of eight saliva collection periods in patients on eradication regimens. During the gastric secretory test, salivary secretions fell in both groups, but only after pentagastrin stimulation (in one collection period in patients on omeprazole, and in three collection periods in patients on eradication therapy). The observed changes in salivary secretion were inversely related to the pre-treatment gastric pH values. CONCLUSION: The influence of omeprazole and omeprazole-based eradication therapies on salivary flow rate is presumably secondary to changes in gastric pH values and is likely to be related to oesophago-salivary reflex generation.

Adult↗
PubMedDate not supplied

[Rectal carcinoid].

Explore the source record for details and available documents.

Aged↗
PubMedDate not supplied

[Endocardial fibroelastosis in children to one year of age].

Out of 2398 autopsies of newborns and infants performed between 1976 and 1985, thirty two cases of endocardial fibroelastosis were found, i.e. 10.6% of the congenital heart diseases in this age group. Endocardial fibroelastosis was most frequent (44%) in infants aged between 3 and 6 months. Seventeen cases of the disease were seen in male infants and 15 cases in female infants. Twenty cases of the endocardial fibroelastosis (62.5%) were of isolated character (primary) whereas 12 cases (37.5%) were of the secondary character associated with other heart abnormalities. Nine cases (about 28%) coexisted with congenital abnormalities of joint and bone system and respiratory tract. A morphologic analysis of the endocardial fibroelastosis with particular reference to its etiopathogenesis suggest its congenital origin or (and) an effect of infection on myocardium. It was also suggested that endocardial fibroelastosis may be a symptom of collagenic disease. About 70% of autopsied infants were hospitalized over 3 days what meant that the course of the disease was severe. Endocardial fibroelastosis was diagnosed clinically only in 6 cases (18.75%).

Endocardial Fibroelastosis↗
PubMedDate not supplied

[Multifocal periventricular leukomalacia in children up to 1 year of life].

The authors present an analysis of the multifocal leucoencephalomalacia in children under 1 year of life based on the material obtained from 2.398 autopsies. It was found that 32 autopsied children suffered from this disease (1.33%). Twenty four of these children were premature. The disease was more frequent in the infants (23 cases) than in neonates (9 cases), and in boys (20 cases) than in girls (12 cases). Multifocal leucoenephalomalacia was manifested mainly as spastic infantile paralysis in the majority of the infants (14 cases). Morphological lesions to the brain most frequently embraced white substance adjacent to the cerebral ventricles (foci of leucoencephalomalacia of 1 cm in diameter) and cerebral vessels. Widening of the ventricular system of the brain was seen in 15 cases. Pathological reaction resulted from the brain anoxia and ischemia in perinatal period (20 cases) or septicaemia (12 cases) while predisposing factors included: prematurity, respiratory failure with hyaline membranes in the lungs and congenital abnormalities of the heart.

Female↗
PubMedDate not supplied

[Coexistence of polycystic kidney and other developmental defects. Analysis of autopsy specimens 1953-1985].

The cases of polycystic disease of kidney selected from 33 years postmortem data were presented. They were classified into 4 types (according to Osathanond, Potter and Heptinstall) and the results correlated with accompanying malformations. It has been established that type I of polycystic disease of kidney was mostly correlated with CNS, skull and spine abnormalities. Type II and III were coexisting with genitourinary and ++gastrointestinal system malformations. No type IV of the disease has been found.

Abnormalities, Multiple↗