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Biomedical subjects

A Kellner

Publications and source records attributed to A Kellner.

24 records · Page 2Linked to original sources
PubMedDate not supplied

A controlled clinical trial of the efficacy of the hepatitis B vaccine (Heptavax B): a final report.

A controlled, randomized, double-blind trial in 1,083 homosexual men from New York confirmed that a highly purified, formalin-inactivated vaccine against hepatitis B prepared from HBsAg positive plasma, is safe immunogenic, and highly efficacious. Over 95% of vaccinated subjects developed antibody against the surface antigen. Vaccine-induced antibody persisted for the entire 24-month follow-up period. The attack rate of all hepatitis B virus infections (excluding conversions of anti-HBc alone) was 3.2% in vaccine recipients compared with 25.6% in placebo recipients (p less than 0.0001). In those who received all three doses of vaccine, of 40 micrograms each, the protective efficacy rate was close to 100%. The vaccine protects against acute hepatitis B, asymptomatic infection, and chronic antigenemia. There is reason to assume that the vaccine is also partially effective when given postexposure.

Adult↗
PubMedDate not supplied

Blood banking as a professional discipline in medicine.

A closer orientation of blood banking toward optimal donor and patient care will depend upon an enlargement of the manpower pool of physicians with specific competence in this area. Toward this end, programs must be developed within medical school curricula, and comprehensive postgraduate training programs must be available for those interested in committing themselves fully to this specialty. Continuing education must be made available to part-time blood banking professionals in order that they remain abreast of newer developments. Recognition of their skills can now come about through competence testing and certification programs. Improvements in management of the blood resource may then be expected to occur in parallel with the increase in numbers and quality of the professionals within this unique specialty.

Allergy and Immunology↗
PubMedDate not supplied

Is blood a commodity?

Explore the source record for details and available documents.

Blood Transfusion↗