Biomedical subjects

A Kayan

Publications and source records attributed to A Kayan.

13 recordsLinked to original sources

PubMed1990

Bilateral sensorineural hearing loss due to mumps.

Viral infections implicated in acute hearing loss include rubella, measles, mumps, herpes zoster, cytomegalovirus and influenza. Mumps' deafness is the best documented disorder. We describe a case where bilateral sensorineural hearing loss, following a severe mumps infection at the age of two, remained unnoticed until the age of four when the patient presented with delayed speech and language. This report emphasises the risk of permanent hearing loss as a complication of mumps infection and discusses strategies for early diagnosis and prevention.

Audiometry, Pure-Tone↗

PubMed1985

Observations upon the evoked responses to natural vestibular stimulation.

Repetitive rotational stimuli simulating natural head movements have been applied to the study of the vestibular evoked response in normal subjects and 12 patients with complete loss of vestibular function. Special precautions were taken to eliminate all possible sources of artefacts, in particular, all eye movements were restrained by requiring the subject to fixate upon a target light attached to the rotating chair throughout the course of the test. With a stimulus of 2 sec duration the typical response took the form of a slow negative wave with a mean peak amplitude of approximately 24 microV and maximally recorded from the vertex. It was characteristically absent in the patient group. Occasionally, both in normal subjects and patients it was preceded by a long latency complex thought to be non-vestibular in origin. Tests carried out both in total darkness and in the light show a statistically significant increase in the potential in the latter condition indicating an influence of the optokinetic effect exerted by the visual surround. Further studies have explored the phase changes brought about by varying the amplitude and duration of the stimulus. These have revealed certain parallels in the results of recent animal experimental studies.

Adult↗

PubMed1984

Neuro-otological manifestations of migraine.

Vestibulocochlear derangements have been studied in three groups of patients: 200 unselected patients with migraine (Series I), 80 migrainous patients referred because of their symptoms for full neuro-otological examination (Series II), and 116 patients with tension headache who served as controls (Series III). Significant differences were established between tension headache and migraine in respect of incidence and severity of symptoms and their time of onset in relation to the headache. In migraine, vestibulocochlear disturbances can occur as an aura, accompanying the headache or during headache-free periods, the highest incidence occurring during the headache. In Series I, 59 per cent reported vestibular and/or cochlear symptoms and these were of disabling severity in 5 per cent. Significantly, 50 per cent had a history of motion sickness and 81 per cent experienced phonophobia during the headache, the probable mechanism of which is discussed. Persisting vestibulocochlear derangements were found in 77.5 per cent of Series II, largely vestibular and of both central and peripheral origin. Involvement of the vertebrobasilar vascular system appears to be the most likely explanation. Possible links between Ménière's disease, benign paroxysmal vertigo and migraine are discussed.

Adolescent↗

PubMed1975