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Biomedical subjects

A Kadioglu

Publications and source records attributed to A Kadioglu.

42 records · Page 3Linked to original sources
PubMedDate not supplied

Evaluation of penile arteries in papaverine-induced erection with color Doppler ultrasonography.

OBJECTIVE: Color Doppler ultrasonography is a useful method in the evaluation of small vessels and vascular anatomy and in demonstrating dynamic changes of blood flow. The detrimental effects of different risk factors of erectile dysfunction such as diabetes mellitus, hypertension, hypercholesterolemia on the penile arterial system were investigated. METHOD: 180 patients with erectile dysfunction underwent functional evaluation of the arterial system by combined intracavernous injection of 60 mg papaverine and stimulation test and color Doppler ultrasonography. RESULTS: There were 64 patients (35.55%) whose vascular findings were normal. A total of 36 patients (20.00%) had arterial insufficiency and 42 patients (23.33%) had mixed-arteriogenic-venogenic impotence. Combination of hypertension and hypercholesterolemia was found to be more detrimental to the penile arterial system than hypertension alone, the presence of hypertension and diabetes mellitus together, diabetes alone and hypercholesterolemia. CONCLUSION: Color Doppler ultrasonography depends on variables such as equipment, operation and software version in the functional evaluation of the penile arterial system. The combination of hypertension and hypercholesterolemia was found to be more detrimental to the penile arterial system. Further studies based on larger patient populations are required in order to determine the effects of erectile dysfunction contributing disease on the penile arterial system.

Arteries↗
PubMedDate not supplied

Combined intracavernous injection of papaverine and stimulation (CIS) test.

The inhibitory effect of the overactivity of the sympathetic nervous system that results from outpatient clinical conditions leads to poor erectile response to intracavernous injection of papaverine. The effects of self manual genital stimulation for improvement of erectile quality in insufficient papaverine response were investigated in 171 impotent men. Twenty-nine (63.04%) of 46 patients who had a normal vascular system showed partial response to papaverine. Following self manual genital stimulation, full erection was achieved in all of them. Better erections were achieved in 28 of 42 patients with arterial disease. In patients subclassified as having slight, moderate, and severe arterial disease, improved erections were noted in 100%, 71.42%, and 64.28%, respectively. In the mixed vascular (arterial+venous) disease group (n = 46), the combined intracavernous injection of papaverine and stimulation (CIS) test led to a better erection in only 41.30%, whereas in the pure venogenic group (n = 37), this percentage was 66.66%. The inhibitory effect of the overactivity of the sympathetic nervous system is significantly reduced by the CIS test.

Adolescent↗
PubMedDate not supplied

The effects of diabetes on penile somato-afferent system.

The direct evaluation of the autonomic nervous system to detect the neurogenic component of erectile dysfunction in men is not possible. Biothesiometry, a vibration perception test, is a simple method for the assessment of the penile somato-afferent system. A nomogram for the evaluation of somato-afferent system has been developed utilizing the biothesiometer in healthy men. This nomogram was used to compare the biothesiometric values of potent and impotent diabetic patients. According to our data, the radix penis is selectively damaged by diabetes mellitus in the first stage of the disease, whereas the glans penis is damaged later on when the disease reaches the stage of impotence.

Adolescent↗
PubMedDate not supplied

The correlation of end-diastolic flow velocity and cavernosometry results in the diagnosis of venous leakage.

OBJECTIVES: Cavernosometry is a conventional and reliable method used in the diagnosis of caverno-venous incompetence. Recently, cavernosal artery end-diastolic blood flow velocity more than 5 cm/sec during the rigid phase and after 10 minutes with duplex ultrasonography has been considered as veno-occlusive dysfunction. METHODS: Fifteen patients with erectile dysfunction aged 20 to 56 years (mean age 35.8) were evaluated by dynamic infusion cavernosometry and duplex ultrasonography which measured end-diastolic blood flow velocity during the rigid phase of erection and after 10 minutes. RESULTS: Dynamic cavernosometry was considered the gold standard during this comparative study. The sensitivity of duplex ultrasonography was found to be 100%, its specificity was 71.42%, positive predictive value 80% and its negative predictive value was 100% in the detection of caverno-venous incompetence.

Adult↗