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Biomedical subjects

A Kably Ambe

Publications and source records attributed to A Kably Ambe.

At least 37 records · Page 2Linked to original sources

[A new parameter for the evaluation of premature luteinization: the pre-ovulatory molecular relation between serum concentrations of progesterone and estradiol].

The objective was to evaluate the molecular ratio between the serum levels of progesterone (P) and estradiol (E2) and to determine it's effect on the in vitro fertilization performance. Sixty two couples were studied, the molecular P:E2 ratio was established the day of human chorionic gonadotropin (hCG) injection. The mean serum P concentration the day of hCG administration 1.45 +/- 0.50 ng/mL, while the mean P:E2 ratio was 0.63 +/- 0. Pregnancies were observed since molecular ration of 0.22, no pregnancies were obtained if the molecular ratio was > 1.02. No significant difference was detected in the fertilization and pregnancy rates in the patients who have or not premature luteinization. The implantation rate was low in patients with premature luteinization, however, there was not significant difference with patients without premature luteinization. In conclusion, the P:E2 ratio surrounding 1.0 is desirable to obtain adequate results in in vitro fertilization programs. In this work as others, the premature luteinization do not have effect in the reproductive results.

Chorionic Gonadotropin, beta Subunit, Human↗

[Analytic study of amniocentesis in prenatal genetic diagnosis. Transversal study of cases].

The experience obtained in 44 cases, in which amniocentesis was practiced for genetic diagnostic purpose in the private center in México City is presented. Indications, morbility and results are similar to those reported in the literature, is considered that this method should be offered to the couples who receive information about it and have maternal age 35 or older, antecedent of family chromosomal disease, alteration in maternal serum screening or family anguish. This is a safe method and easy to perform with a high sensibility and specificity, this is the first report in a private center in México that analyzes technique.

Adult↗

[A physiopathological overview of climacteric and menopause].

Today, million of woman in the world lived enough to experience the menopause ant it's seculae. In the last few years the research of the events associated with this age has gained enormous attention. Hormonal replacement therapy has been shown to reduce the incidence of cardiovascular disease, osteoporosis and other complications in postmenopausal woman. In this paper we review the endocrinology of the menopause, benefits and risks of hormonal replacement therapy, Prescription choices, compliance and health care professional attitudes are too analysed.

Adult↗

[A murine model of polycystic ovaries: its use in the evaluation of effects of endoscopic ovulation induction].

The objective was to evaluate the effect of the endoscopic treatment of the polycystic ovary syndrome (PCOS) in a murine model induced with depot estrogen. Three groups with PCOS were studied: group 1 (n = 22) evaluated exclusively using laparoscopy; group 2 (n = 11) one fulguration on both ovaries was performed during laparoscopy; and group 3 (n = 10) three fulgurations were performed. One month after laparoscopy the animal were sacrificed and was carried surgical microscopic examination of the intraabdominal organs, moreover histological evaluation of the gonads was practiced. All the animals showed PCOS. No adhesions were observed in the animals of group 1, while the frequency of adhesion in group 2 was 36.3%, 18.1% of the animals of group 2 showed gonadal atrophy. The frequency of adhesions in the group 3 was 66.6%. The adhesion score was significantly higher in groups 2 and 3 than in group 1. Is concluded that the use of estrogen is useful to induce PCOS in animal models. The procedure can be employed to study the effects of the surgical induction of ovulation, it's utility in other conditions seems promissary.

Animals↗

[Prognostic importance of controlled ovarian hyperstimulation previous to therapeutic laparoscopy of infertile patients].

The use of the laparoscopic approach in the initial evaluation of the infertile couple without obvious disease is controversial; for these reason some centers has been done the initial treatment with ovarian stimulation (OS). The present article analyze two groups, the first for patients with OS for 4 cycles and laparoscopic approach after that and the second group with initial laparoscopy and medical treatment if they need it. Both groups has a OS after the laparoscopic procedure. The analysis of the prognosis of the OS before the laparoscopy and the impact in the reproductive outcome is done. The results shows that the OS does not have deleterious effects of the pregnancy rates if it is used before the procedure. However, the pregnancy are present early in the second group P < 0.05. In conclusion, in infertile woman without obvious disease that indicate the laparoscopy, the initial use of OS before the laparoscopy does not have a deleterious impact on the pregnancy rates.

Adult↗

[Integral treatment of severe ovarian hyperstimulation syndrome by means of autotransfusion of ascitic fluid and intravenous infusion of albumin].

Severe ovarian hyperstimulation syndrome (OHSS) is a potential life-threatening condition relationated with ovulation induction. It affects multiple systems. Little is known about it's pathophysiology. The treatment available consists in the correction of fluid, electrolyte and hematologic imbalances. In other hand, is mandatory the prevention of embolic phenomena. Ascitic fluid aspiration result in dramatic improvement of symptoms. The purpose of this study was to assess the effect of autotransfusion of ascitic fluid obtained by paracentesis and the intravenous infusion of albumin for the treatment of severe from of the OHSS.

Adult↗

[Gynecologic laparoscopy at the ABC Hospital. Analysis of 882 cases].

The objective was to evaluate the indications and clinical evolution of patients treated with laparoscopy. Eight hundred eighty two women undergoing conventional laparoscopy for gynecological pathology, patients were not preselected, preoperative and postoperative data were registered retrospectively. Main indications to perform laparoscopy were dismenorrhea and infertility. Endometriosis and pelvic adhesions were the most frequent findings detected in the study subjects. Endoscopic treatment resulted in minimal complications and short postoperative stay. As conclusion classic laparoscopy is a safe and efficacious technique for treatment gynecological pathology.

Adolescent↗

[Clinical evaluation of patients treated with open gynecologic laparoscopy].

The objective was to evaluate the clinical evolution and rates of complications for open gynecological laparoscopy. Were studied the records of ninety two patients treated with open laparoscopy for gynecological pathology. The major indication for performing laparoscopy was infertility management. There were not early or late complications of trocar insertion or operative laparoscopy. As conclusion, in the studied group open laparoscopy can to eliminate the risks of blind insufflation and trocar insertion observed in the classical technique, is a safe and efficacious method to treat several gynecological pathologies.

Adult↗

["Initial results of the first ambulatory program for in vitro fertilization in Mexico"].

Infertile couples treated with in vitro fertilization and embryo transfer (IVF-ET) seeking highest standards of case. The new programmes of IVF-ET are under pressure to generate as quickly as possible acceptable pregnancy rates. We report our experiences at a new IVF clinic, performing conventional IVF-ET and oocyte donation. Patients were treated in groups, their menstrual cycles were previously synchronized with luteal phase noretisterone. Both variants of IVF produced clinical pregnancies since the start of activity. In this paper the logistic and methodology are discussed. Today the aim of the programme is increasing the efficiency and efficacy of same.

Adult↗

[Intestinal endometriosis as an acute surgical emergency].

Endometriosis is rarely found by the general surgeon and sometimes it may seem a surgical disease. Two cases with abdominal pain, requiring surgical treatment, are presented. The first case gave history of dysmenorrhea and dyspareunia, she was admitted with acute abdomen due to acute appendicitis, and laparoscopic appendectomy was performed without complications; she had slight endometriosis at left utero-sacrum ligament and histopathological report showed endometriosis at the appendix. The second patient presented with incomplete obstruction related to ileocecal damage that it was resected with an histopathological report of endometriosis at cecum, ileon and appendix. The patient presented with endometriosis, degree IV, and had medical treatment with gestrinohn, during six months; latter on, HTA+SOB, was done, she received hormonal therapy. Endometriosis may be a cause for acute abdomen in women, and it should be considered in the differential diagnosis.

Acute Disease↗

[New perspectives for an old problem: premature labor].

Preterm birth has been and continues to be one of the most serious problems in Obstetrics. It is the most common cause of neonatal death, and morbidity in surviving infants. The presence of bacterial vaginosis, and other genital infections is associated with increased risk of preterm labor. Cytokines promote the release of prostaglandin, and have been implicated as cause of uterina activity. Recently, new methods of detection as transvaginal ultrasonography, and measures of cervical fetal fibronectin have been acclaimed as useful to detect the problem. Atosiban, cytokines, glyceril trinitrate, and many others agents have been proposed as treatments and are under investigation. Such drugs, will allow an effective management of preterm labor with lower side effects. Antenatal TRH administration cannot be recommended for widespread clinical use. However, the antenatal administration of corticosteroids to fetuses at risk of preterm delivery include not only a reduction in the risk of respiratory distress syndrome but also a significative reduction in intraventricular hemorrhage mortality.

Adolescent↗

[Pharmacologic suppression of the ovarian function and its clinical usefulness].

The gonadotropin-releasing hormone (GnRH) is essential in human reproduction. By modification of the molecular structure of the original hormone, analogues were synthesized with agonistic or antagonistic effects. GnRH agonists have high binding affinity for receptors, and their prolonged or continuous use resulted in inhibition of LH and FSH release. On the other hand, GnRH antagonists have an entirely different mechanism of action but still suppress gonadotrophin release. Currently, the use of analogues of GnRH is an established therapy for hormone-dependent diseases and other clinical conditions.

Female↗

[Vaginal hysterectomy assisted by laparoscopy. Critical and comparative study if vaginal and abdominal hysterectomy at the A.B.C. Hospital of Mexico].

The laparoscopically assisted vaginal hysterectomy offers the possibility to convert abdominal to vaginal approach give to the patient the benefits of ti. The analysis of the first 20 cases in our institution is done and are compared with abdominal and vaginal approaches in some parameters including costs, indications and hospitalization days. The laparoscopically assisted vaginal hysterectomy offers to the patient the benefits of the vaginal approach with hospital stay similar and cost and operative time higher than those for either vaginal and abdominal hysterectomy. The exact role of the laparoscopically assisted vaginal hysterectomy on daily practice still is pending.

Adult↗

[Efficacy of a program of insemination with cryopreserved semen as treatment of the male factor].

The purpose of the present study is to determine the efficacy of an artificial insemination program with frozen donor sperm as an alternative therapy for male factor infertility. Twenty six women underwent 86 insemination cycles with frozen donor sperm. Clomiphene citrate or human menopausal gonadotropins were utilized for ovulation induction; human chorionic gonadotropins, 10,000 IU, was administered with one or more dominant follicles > or = 16 mm; intrauterine insemination was performed 36 hours after the injection. The pregnancy rate per cycle was 16.6%, and the cumulative pregnancy rate was 58.3%. It is concluded that intrauterine insemination with frozen donor sperm is a good alternative, instead of adoption, for male factor infertility with no available treatment.

Adult↗

[2 cases of abdominal endometriosis].

Abdominal wall endometriosis usually occurs in the surgical scar of previous cesarean sections. This condition often presents as a mass with cyclical pain and swelling. Two cases of abdominal scar endometriosis are reported. The definitive diagnosis was established by pathologic analysis. Both patients were premenopausal with no history of endometriosis. Pelvic endometriosis was not detected in the patient undergone laparotomy. The management consisted in perform and adequate excision to prevent recurrence. The utility of drug therapy is evaluated.

Abdominal Muscles↗

[Cytologic-colposcopic-histopathologic correlations in preinvasive cervical lesions and cervical Human Papillomavirus infections].

Cervico-uterine cancer is the most frequent gynecological neoplasia in Mexico and cervico-vaginal cytology is the most practical and dependable resource in lesions detection. During the last years precursory lesions detection (NIC and HPV infection) has increased. So, every patient presenting with an abnormal cytology should be included in an evaluation program, that includes a colposcopic study with biopsy of suspicious lesions, in order to know cellular abnormality degree, as these studies combination increases diagnosis certainty. Ninety three patients were evaluated by colposcopy, as the Papanicolaou showed abnormality ICN type in any degree or HPV infection data, during the first three years of the Unidad de Colposcopia de la Beneficiencia del Hospital ABC. In 49 patients histopathological study, was done. A correlation of all studies was carried out. There was a correlation cytology-histopathology of 59.18%; and colposcopy-histopathology of 89.79%. It was concluded that evaluation by cytology is insufficient to establish a final diagnosis and treatment, and that colposcopic study is fundamental in the evaluation of the patient with abnormal exfoliative cytology.

Adult↗

[Analysis of the predictive value of prolactin concentration in the umbilical cord as an evaluation parameter for respiratory insufficiency in the newborn].

In fetal pulmonary development several substances and hormones which directly participate, have been involved. One of these is prolactin, which by raising concentrations through a complex mechanism seems to participate in pulmonary maturation. Due to the importance of product's pulmonary maturity producing respiratory failures of the newborn, some progress has been made in opportune diagnosis, and mainly in prophylaxis of this condition. In this study, serum samples were taken from the umbilical chord to know perinatal evolution after analysis of the evolution of each of the 37 cases, the results corresponded to previous results as published in literature for different conditions as toxemia, diabetes mellitus or prematurity, as well as the relationship between hormonal serum concentrations, and gestational age and weight.

Adult↗

[Endometriosis. Analysis of laparoscopic findings at the A.B.C. (American-British Cowdray) Hospital].

Endometriosis approximately affects 10 to 15% of premenopausic women. Diagnosis mainly is made by laparoscopy. We revised all the laparoscopies which were made in labor service at the American British Cowdray Hospital from July 1st 1989 to June 30th 1994 in order to evaluate the incidence of endometriosis in the institution. They were made from 882 laparoscopies done, in 447 cases (50.68%) endometriosis was the main finding, this was similar to the reports published by other authors. The group of age mainly affected was from 20 to 29 years-old. Sterility was found in 53% of these patients, slightly above the results in other series. The 85% of the cases were in hospital for less than 24 hours. Complications were in 7% of them, none required a laparotomy, however.

Adnexal Diseases↗