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Biomedical subjects

A K Yates

Publications and source records attributed to A K Yates.

35 records · Page 2Linked to original sources
PubMed1975

Prophylactic antibiotics in open heart surgery.

Two prophylactic antibiotic regimes were compared in 129 patients who had open heart surgery for mitral and/or aortic valve replacements at Guy's Hospital. The first group were prescribed cephalothin for five days beginning with premedication. The second group were prescribed the combination of cloxacillin and gentamicin for the same time. The incidence of minor infection was low. There was no statistical difference between the two antibiotic regimes. The major infections were due predominantly to Gram negative organisms and difficult to prevent by any prophylactic regime.

Adolescent↗
PubMed1975

Surgical treatment of ventricular tachycardia after epicardial mapping studies.

Two patients with intractable life-threatening ventricular tachycardias have been studied using intracardiac electrograms and programmed electrical stimulation of the heart. Both patients have shown to have an underlying re-entry mechanism in the ventricles as the basis for the tachycardias. Both patients underwent epicardial mapping studies at cardiac surgery, and the site of re-entry was established. In one patient the re-entry front was found to start in the posterobasal region of the left ventricle and in the other patient the re-entry front was found in the anterobasal region of the right ventricle. In both patients surgical interruption of the re-entry front was carried out. Both patients are alive and free from tachycardias at the time of writing.

Adult↗
PubMedDate not supplied

Doppler ultrasound assessment of the internal carotid artery following carotid endarterectomy.

Doppler-shifted ultrasound with spectral analysis was used to assess the internal carotid arteries of 48 patients who had undergone carotid endarterectomy (58 carotid endarterectomies). Three patients died in the immediate post-operative period, therefore 45 patients, who represented 54 endarterectomies, were assessed for up to six years following surgery (mean--thirty-four months). Ultrasound tests demonstrated total occlusion of the internal carotid artery in 7 patients within the first post-operative week. Sonograms from the supraorbital and common carotid arteries exhibit two peaks during cardiac systole (A and B). The post-operative A/B ratios were abnormal in 24 instances and these were associated with symptoms in seven. Of these 24, 7 developed severe disease in the internal carotid artery during the six year follow-up period; five were associated with symptoms. Post-operative A/B ratios were normal in 23 instances, 19 of which remained normal at follow-up. None of these nineteen developed symptoms. Only patients with abnormal post-operative A/B ratios subsequently developed severe occlusive disease in the internal carotid artery during the follow-up assessment. Thirty-eight patients underwent unilateral carotid endarterectomy, eight of whom had severe internal carotid artery disease at the contralateral bifurcation at the time of carotid endarterectomy. A further four patients developed severe occlusive disease in the contralateral internal carotid artery during the follow-up period, one of whom was symptomatic.

Adult↗