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Biomedical subjects

A K Shapiro

Publications and source records attributed to A K Shapiro.

At least 37 records · Page 2Linked to original sources

The Hopkins Symptom Checklist (HSCL)--factors derived from the HSCL-90.

A factor analysis of the 90-item version of the Hopkins Symptom Checklist, performed on the pretreatment self-ratings of nonpsychotic outpatients with symptoms of depression and anxiety, revealed the presence of 8 clinically meaningful factors. These eight orthogonal factors each contained at least 5 items with loadings above 0.40 and explained 4.5% or more of the matrix variance. They were labeled Somatization, Phobic-Anxiety, Retarded Depression, Agitated Depression, Obsessive-Compulsive, Interpersonal Sensitivity, Anger-Hostility and Psychoticism.

Adolescent↗

Gilles de la Tourette's syndrome: clinical, genetic, psychologic, and biochemical aspects in 21 selected families.

Eighty-one patients and relatives with Tourette's syndrome, members of 21 selected families, participated in a 1-day clinic. In 12 of the 13 Jewish families and six of the eight non-Jewish families, there were multiple members with motor and vocal tics by observation or history. Males predominated among those with persistent symptoms, but among those with spontaneous clearing, females predominated. Twelve propositi had troublesome sexual and aggressive impulses, differing only quantitatively from normal. No evidence of abnormality was found in plasma dopamine beta hydroxylase, or norepinephrine levels.

Adolescent↗

The behavior therapies: therapeutic breakthrough or latest fad?

The author critically examines the evidence for the effectiveness of the behavior therapies as described in the American Psychaitric Association's task force report on behavior therapy. He concludes that current attempts to evaluate behavior therapy suffer from inadequate methodology and that the claims for its therapeutic efficacy are excessive and unsupported by the controlled clinical evidence.

Behavior Therapy↗

Prognostic correlates of psychotherapy in psychiatric outpatients.

The authors examined the follow-up data for 113 psychiatric outpatients who had been treated for up to a year in an outpatient community mental health center. Correlations between therapist and patient ratings of improvement were generally low, and anlayses were done separately for therapist and patient ratings. The strongest confirmed hypothesis was the relationship between therapist and patient ratings of improvement and therapist and patient evaluations of each other as likable, physically attractive, and either a good patient for treatment or a competent therapist. The authors discuss the advantages and disadvantages of multivariate statistics for the analysis of psychotherapy data.

Ambulatory Care↗

A follow-up of 78 patients with Gilles de la Tourette's syndrome.

The authors conducted a follow-up study of 78 patients with Gilles de la Tourette's syndrome. Four of the patients were in spontaneous remission; 59 patients taking haloperidol showed an average improvement of 79.3% and the remaining patients, 3 of whom were taking medication other than haloperidol and 12 of whom were not taking any medication, showed an average improvement of 24.7%. Side effects were the main cause of discontinuing haloperidol. The authors found that response to haloperidol was unrelated to family history of tics, age at onset, type or severity of symptoms, or signs of organicity.

Female↗

Correlates of placebo reaction in an outpatient population.

Variables describing 113 outpatients of a mental health clinic were derived from a Placebo Test, the MMPI, a Symptom Check List, measures a response style, and a questionnaire containing historical and demographic information. Two highly reliable scales, the Placebo Effect Scale (PES) and the Side Effect Scale (SES) were derived from the Placebo Test and served as dependent variables. PES scores were inversely related to reporting symptoms and unrelated to measures of response style. SES scores were directly related to reporting symptoms and with several measures of response style. There was a curvilinear relationship between placebo response and reporting side effects. Implications of results for further research are presented.

Adolescent↗