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Biomedical subjects

A K Marsden

Publications and source records attributed to A K Marsden.

29 records · Page 2Linked to original sources

The use of computerized echoencephalography after recent head injury presenting to the accident and emergency department.

In a review of the records of 874 head-injured patients who had an echoencephalogram in the Accident and Emergency Department, two patients with apparently 'minor' head injury subsequently developed an extradural haematoma. Both would have been diagnosed earlier if the results of the echoencephalogram had been used to influence their referral to the nearest neurosurgical department before the onset of any neurological deterioration. For those patients who arrive in the Department in coma, failure to detect any midline shift should not delay urgent referral for a CT scan. Such patients may be harbouring either bilateral haematomas or a very large single haematoma causing more than the 14-mm maximum shift recordable by the equipment.

Adolescent↗

The effect of head restraints and seat belts on the incidence of neck injury in car accidents.

During a 5-month period a study was made of motor vehicle occupants presenting at an Accident and Emergency department following an accident. Records were made of the incidence of neck injuries in relation to the presence of head restraints and the use of seat belts. There was a slight reduction in injuries when a head restraint was fitted but this difference did not achieve statistical significance. The incidence of neck injury was not increased if a seat belt was worn. It may be that the reason for the failure of head restraints to afford the expected protection is their inappropriate design and lack of adequate adjustability.

Accidents, Traffic↗

Aerobic and anaerobic bacteriology of subcutaneous abscesses.

Pus from 84 patients with subcutaneous abscesses was examined for aerobic and anaerobic bacteria: organisms were recovered from 70 (83.3 per cent). In 13 no organisms were seen in the Gram-stained smears and the cultures showed no bacterial growth. Staphylococcus aureus was the most prevalent organism (n = 44), isolated in 43 in pure culture, in marked contrast to the anaerobic organisms which almost invariably were associated with mixed cultures. All patients were treated by the primary suture method. Half of them were not given preoperative antibiotics and 3 developed bacteraemia and 1 septicaemia. Blood isolates were of S. aureus of the same phage type as pus isolates. The other patients received one infection of 300 mg of clindamycin phosphate 30 min to 1 h before surgery. From this group only one patient, with a perianal abscess, developed Escherichia coli bacteraemia. The levels of clindamycin in the abscess aspirate were inhibitory for S. aureus, bacteroides, streptococci and other Gram-positive bacteria but not for E. coli.

Abscess↗

Antibiotics in surgical treatment of acute abscesses.

A four-way, double-blind, prospective trial of treatment of abscesses by incision, curettage, and primary closure with and without antibiotic cover (clindamycin injection before operation or capsules after operation, or both) was conducted. There was no appreciable difference in mean healing time between the patients given both the antibiotic injection and the antibiotic capsules and those given the injection and placebo capsules, whereas healing times in those given the placebo injection and antibiotic capsules or placebo only were appreciably longer. Four of the patients who were not given the antibiotic injection developed bacteraemia; one patient who was given the antibiotic injection also developed a bacteraemia, but this was caused by clindamycin-resistant bacteria. These results show that a single injection of an effective antibiotic before operation is sufficient to protect the patient against bacteraemia and permit optimum healing.

Abscess↗

Entonox in the emergency department.

The use Entonox (BOC Medishield) was examined in a large accident and emergency department and was found to give satisfactory relief from pain in 92 per cent of cases. This compares favourably with reports of its results in other applications.

Adolescent↗