Myelofibrosis with myeloid metaplasia due to tuberculosis.
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Humans↗
Biomedical subjects
A K Majumdar
Publications and source records attributed to A K Majumdar.
High-performance liquid chromatographic methods for the determination of a new carbapenem antibiotic, L-749,345, in human plasma and urine.
A column-switching, reversed-phase high-performance liquid chromatographic (HPLC) method for the determination of a new carbapenem antibiotic assay using ultraviolet detection has been developed for a new carbapenem antibiotic L-749,345 in human plasma and urine. A plasma sample is centrifuged and then injected onto an extraction column using 25 mM phosphate buffer, pH 6.5. After 3 min, using a column-switching valve, the analyte is back-flushed with 10.5% methanol-phosphate buffer for 3 min onto a Hypersil 5 microm C18 BDS 100x4.6 mm analytical column and then detected by absorbance at 300 nm. The sample preparation and HPLC conditions for the urine assay are similar, except for a longer analytical column 150x4.6 mm. The plasma assay is specific and linear from 0.125 to 50 microg/ml; the urine assay is linear from 1.25 to 100 microg/ml.
Anti-Infective Agents↗
Diagnostic aspiration of hydatid cyst of liver--changing view.
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Adult↗
Colchicine in diabetes mellitus.
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Anti-Inflammatory Agents↗
Klebsiella pneumonia with lung abscess in a male child.
An unusual presentation of Klebsiella pneumonia with lung abscess in a male child with no apparent predisposing factor is described.
Child↗
Preliminary evaluation of a new psychotropic drug, lenperone, in the treatment of acute schizophrenia.
An open trial of a new psychotropic drug, lenperone, was carried out in 10 patients with acute schizophrenia. The duration of treatment was 28 days and the maximum dose administered was 60 mg per day. A pronounced antipsychotic effect was seen in half of the patients, although all 10 patients showed a pharmacological response to the drug. The incidence of side-effects was low. Haematological, biochemical and electrocardiographic tests failed to demonstrate any abnormality due to treatment.
Acute Disease↗