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Biomedical subjects

A K Hati

Publications and source records attributed to A K Hati.

At least 19 recordsLinked to original sources
PubMed1996

Effect of DDT on Phlebotomus sandflies in Kala-Azar endemic foci in West Bengal.

Phlebotomous argentipes, the vector of Kala-azar was found susceptible to DDT and found to reappear in the nine months after one time DDT spray at the rate of lg/m2 in three endemic foci of districts North and South 24-Parganas of West Bengal. Ph. papatasi, the other predominant species found resistant to DDT appeared within one month of DDT spray.

Animals↗
PubMed1995

Indoor resting anophelines of north Bengal.

A systematic survey was carried out between April 1993 and March 1994 to study the distribution and prevalence of anopheline mosquito species in two malaria-prone areas situated in the foothills of Darjeeling district. Ten different species of Anopheles viz. An. aconitus, An. annularis, An. barbirostris, An. culicifacies, An. fluviatilis, An. hyrcanus group, An. maculatus, An. subpictus, An. vagus and An. varuna were collected. Per man hour density of mosquitoes collected was 4.5 and the most prevalent species was An. vagus, comprising 63% of the total catch. An. fluviatilis, an efficient vector of malaria in the foothill regions of India, was reported for the first time from this area. However, the classical vector of this region viz. An. minimus was altogether absent during the course of the present survey. All the ten species were found in cowsheds while, human habitation harboured higher population density (56.5%) of the total catch.

Animals↗
PubMed1995

Transmission of Sarcoptes scabiei from animal to man and its control.

Outbreak of Sarcoptes scabiei in animals spilling over to man in close association was observed in two adjacent villages, Fewgram and Nurpur in the district of Birbhum, West Bengal, from mid-November to mid-December, 1991. Nineteen goats and one calf who did not receive any treatment died of sarcoptic manage. All infected animals got cured with external application of deltamethrin, a synthetic pyrethroid and triazapentadiene. Human cases were treated successfully with benzene hexachloride (2%).

Adult↗
PubMed1995

An institutional outbreak of hepatitis E--reported first time from Calcutta city.

A sudden outbreak of hepatitis occurred in a micro-epidemic form, amongst the staff members of the School of Tropical Medicine, Calcutta, during May-June, 1995. A total of 21 persons developed jaundice, out of whom 11 members who attended the Virology Department and were tested for detection of different serological markers of hepatitis by ELISA. All the sera (N = 11) showed evidence of non-A, non-B infection by process of exclusion and 9 of the above sera showed evidence of anti-HEV when tested specifically. This is the first documented outbreak of viral hepatitis in respect of Calcutta.

Adult↗
PubMed1995

Susceptibility status of Phlebotomus argentipes to DDT, dieldrin and malathion in Hoogly, West Bengal.

Susceptibility tests were carried out with DDT (4%), dieldrin (0.4%) and malathion (5%) using the WHO test kits against Phlebotomus argentipes sandflies collected from Dankuni, situated in Hoogly district, 21 km from Calcutta, West Bengal. P. argentipes was found to be susceptible to all the three insecticides tested. LT 50 was calculated to be 10.6 minutes, 10.2 minutes and 2.8 minutes for DDT, dieldrin and malathion against the flies.

Animals↗
PubMed1995

Anophelines of Siliguri-Naxalbari block, Darjeeling, West Bengal.

A systematic survey has been carried out during 1993-94 to study the occurrence and distribution of anopheline mosquitoes in Siliguri-Naxalbari block of Darjeeling district. The anopheline fauna of this region consists of 13 species, namely, An. vagus, An. culicifacies, An. annularis, An. barbirostris, An. subpictus, An. maculatus, An. tessellatus, An. jamesii, An. aconitus, An. "hyrcanus" group, An. karwari, An. fluviatilis and An. jeyporiensis among which the first five species forms the major bulk (92%). All the species showed preference to cattlesheds than human-habitation for resting. The ratio between morning and evening collection was 1:0.87.

Animals↗
PubMed1994

A simple medium without blood modified for successful isolation & cultivation of LD bodies.

A simple growth medium for primary isolation and subsequent cultivation of Leishmania donovani promastigotes without using whole blood is described. This medium is modified from Aljeboori's biphasic medium (used originally only for cultivation), containing only beef extract, peptone, sodium chloride, bactoagar and foetal calf serum (FCS). We have modified the medium by adding glucose and ascertaining the pH in the solid phase and by drastically reducing (91%) FCS in the liquid phase. The medium helps in isolation of L. donovani promastigotes from kala-azar patients, in addition to luxurious growth of parasites. The medium is simple, reliable, reproducible and convenient, with minimal interference in using the parasitic cells for immunological, molecular and isoenzyme studies.

Animals↗
PubMed1993

Neutralization of pathophysiological manifestations of Russell's viper envenoming by antivenom raised against gamma-irradiated toxoid.

Rabbits were immunized against gamma-irradiated (100 krads) Russell's viper venom toxoid adsorbed to aluminium phosphate gel. The antivenom (0.1 ml) neutralized 5 LD50, 8 minimum hemorrhagic doses (MHD) and 14 minimum necrotic doses (MND) of venom. The coagulant and protease activities of the viper venom were neutralized more effectively than phospholipase A activity, by the toxoid antivenom.

Animals↗
PubMed1993

Correlation between the preferred biting site of Culex quinquefasciatus and the region of the body affected by clinical filariasis.

Entomological and filariasis surveys were conducted simultaneously in a rural and an urban environment in West Bengal from September 1986 to August 1987. The aim of the surveys was to see if any correlation existed between the preferred biting site of Culex quinquefasciatus, the filarial vector, and the region of the body affected by clinical filariasis. Significantly more mosquitoes (> 55%) attacked the thighs, legs and feet of human volunteers than other sites on their bodies, whether the volunteers were indoors or outdoors, in rural or urban environments. Significantly more patients had clinical filariasis of these lower body parts than of the upper parts. The vector's preferred biting sites and the anatomical sites most affected by clinical filariasis were therefore the same.

Adult↗
PubMed1993

Sarcoptes scabiei in animals spreading to man.

An outbreak of Sarcoptes scabiei in animals was observed from mid-November 1991 to mid-December 1991 in two adjacent villages, Fewgram and Nurpur, in Birbhum District, West Bengal State, India, starting from goats to cattle, then to sheep and even to dogs. Nineteen goats and one cattle died of manage infection. The infection spread to man in the last week of December 1991, and affected forty-two human beings, tending and rearing animals. The animals treated with deltamenthrin (synthetic pyrethroid) and amitraz (triazapentadiene) were completely cured. In man, the disease seemed to be self-limited in some cases and 2% hexachlorobenzene was successfully used for treatment of the others. The outbreak was effectively controlled in March 1992.

Adult↗