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Biomedical subjects

A K Hansen

Publications and source records attributed to A K Hansen.

46 records · Page 3Linked to original sources
PubMed1990

Epidemiological studies of Bacillus piliformis infection and Tyzzer's disease in laboratory rats.

Characteristics in connection with the presence of Bacillus piliformis in the barrier-protected animal rooms of a breeding centre for laboratory rats are discussed. The incidence of antibodies against B. piliformis in IFA test is high -77.8% for the total breeding centre. Clinical and pathological changes are, however, rare and mainly connected with certain rat strains. Immunosuppression with prednisolone and subsequent histopathological tests of liver sections indicate that rats with MHC-type RT1.A-u have an increased risk of developing Tyzzer's disease, while RT1.A-1-carriers seem to be resistant to this disease.

Animals↗
PubMed1990

Profundaplasty as the only reconstructive procedure in patients with severe ischemia of the lower extremity.

Twenty-one profundaplasties were performed as the only reconstructive procedure. All of the patients had severe ischemia of the lower extremity with serious symptoms, such as rest pain or gangrene, or both. There was no postoperative mortality. Two patients had a crural amputation, and one patient, a femoral amputation performed during the first three months postoperatively. All of the other patients improved, and there was a significant rise in distal blood pressures after one week, further increasing after three months. At follow-up study, 15 of the patients had considerably less symptoms than preoperatively or were free of symptoms. There was a limb salvage rate of 83 per cent after 60 months. The operation is recommended whenever possible in patients with severe ischemia of the lower extremity when the possibilities of other reconstructive procedures are considered to be poor.

Aged↗
PubMed1989

[Social aspects of reconstructive vascular surgery in patients under 60 years of age].

The effect of initial elective arterial reconstructive surgery was evaluated in relation to employment and social status. Ninety patients with intermittent claudication were followed for a period of 3.5 years. The male to female ratio was 1:12. At the time of operation, all the patients were under the age of 60 years and potentially professionally active. The indication for operation in fifty-nine patients was intermittent claudication. For thirty-one patients, the indication for operation was ischaemic rest pain, gangrene or ulcer. Fifty-six patients (74%) returned to active employment following vascular reconstructive surgery. It is concluded that reconstructive vascular surgery is of great importance for rehabilitation and in the success of resumption of active employment.

Adult↗
PubMed1989

Serum and urinary phosphate during and after prolonged muscular ischaemia in non-exercising men and women.

Serum inorganic phosphate (Pi) concentrations and urinary Pi excretions were measured in nine patients undergoing abdominal aortic bypass grafting (group I) and in nine patients undergoing lower limb arterial embolectomy (group II). In group I, serum Pi concentrations were normal until 24 h after reperfusion, when they decreased, reaching their nadir at 48 h (median Pi 0.45 mmol 1(-1). The urinary phosphate clearance relative to the creatinine clearance (Cp/Cc) increased 5 min after reperfusion reaching a maximal median value (0.454) in the 2-24-h collection period. In group II, eight patients had a normal and one had a subnormal serum Pi before reperfusion. None developed hypo- or hyperphosphataemia and the Cp/Cc remained unchanged. Daily urinary Pi excretion was higher in group I than in group II (P less than 0.03). The authors concluded that the regional muscular ischaemia in non-exercising men and women was not associated with hyperphosphataemia. The possible influence of major surgery and anaesthesia on phosphate homeostasis should be considered.

Aorta, Abdominal↗
PubMed1989

Operative pleurodesis in spontaneous pneumothorax. Indications and results.

In 61 cases of spontaneous pneumothorax treated with thoracotomy and pleurodesis, sometimes with resection of bullous lung tissue, the records were reviewed. There were few postoperative complications and no treatment-requiring recurrences. The postoperative drainage time was significantly longer in patients with, than in those without, chronic obstructive pulmonary disease preoperatively, but the long-term results were the same in both groups. Age did not influence the results. The treatment policy in this selected group of patients seemed to be highly satisfactory.

Adult↗
PubMed1988

Popliteal arterial aneurysm.

Popliteal arterial aneurysms are rare in young individuals. A case without a penetrating trauma presenting in a young woman is described. Complications may lead to vascular emergencies. Early diagnosis and surgical treatment is important.

Adolescent↗