Search PubMed⌕ Search

Biomedical subjects

A K Gus'kova

Publications and source records attributed to A K Gus'kova.

At least 19 recordsLinked to original sources
PubMed2006

[Radiation medicine and its significance to scientific and practical internist's activity].

The author of the article analyzes the significance of radiation medicine in the system of medical sciences, and stresses that radiation medicine and other fields of medicine have a lot of common points in their interests and the ways of development. All these points concern patients and problems of the evaluation of their health status in connection with diverse forms of radiation contacts. The author discusses the reliability of the sources of information and the forms of data presentation in the main publications addressed to certain groups of medical practitioners, researchers, and healthcare managers. The most significant results of radiation medicine, which may be useful to clinical medicine in general, are summarized in the article. The author annotates and assesses the targeting of manuals of radiobiology and radiation medicine issued in the resent years.

Adult↗
PubMed2004

[Case of chronic radiation sickness with subsequent leukemia in track driver subjected to long-external gamma-irradiation (cesium-137)].

The article deals with consequences seen in track driver after prolonged exposure to radiation caused by "lost" gamma-source (cesium-137) that long remained in receptacle of the vehicle's left door. Radiation dose averaged 8 Gy. The authors presented clinical manifestations, changes in peripheral blood and bone marrow, cytogenetic data by progression of radiation hemopoiesis hypoplasy to myelodysplastic syndrome and to acute leukaemia.

Adult↗
PubMed1997

[Causes of death of persons exposed to health hazards in the area of the Chernobyl Accident].

Causes of death were analysed for two groups of subjects exposed to radiation in 1986 because of the Chernobyl accident. 27 victims were exposed to external gamma-radiation (4.3-13.7 Gy) in the moment of or few hours after the accident. Most of these subjects had radiation sickness of different severity in combination with local radiation lesions. 2 victims had severe thermal burns. 405 victims worked as wreckers or emergency teams members in the contaminated area in different time after the accident. They died most frequently of traumas, accidents, cancer, cardiovascular diseases. Most of deaths in this group were attributed to general somatic causes unrelated to the hazards of the ionizing radiation.

Adult↗
PubMed1992

[Current problems of clinical radiation medicine].

Results, prospects of studying the effects of ionizing radiation on human beings are considered with regard to the outcomes of the Chernobyl catastrophe and the results of a 5-year implementation of the All-Union Programme C-27. Present-day problems and approaches to investigation for the nearest 5-year period are formulated.

Accidents↗
PubMed1991

[Malignant neoformations of the hematopoietic and lymphoid tissues in the personnel of the 1st plant of atomic industry].

Rates of mortality from hemopoietic and lymphoid malignancies for 1948-1987 were studied in male staff of industrial atomic reactors and radiochemical industry for irradiated uranium processing versus dose of external gamma radiation. An increase in mortality due to radiation--induced acute leukemia was registered in the radiochemical industry staff 5-10 years following the start of exposure and was associated with high dose of external radiation. The risk of acute leukemia for this period was 1.65 x 10(-3) x Sv-1 cases during 5 years whereas within the other 30-35 years of follow-up the risk of death from hemolymphoblastosis or acute leukemia was less than 1 x 10(-3) x Sv(-1) during 5 years.

Hodgkin Disease↗
PubMed1991

[Surgical treatment of radiation injuries of the hand].

An analysis is given to pilot experience with up-dated plastic surgery techniques in management of hand radiation injuries. Seven patients underwent surgery involving cross-over skin, scapular, radial and inguinal grafts, sliding Littler island graft. The results (both short- and lond-term) turned promising.

Dermatologic Surgical Procedures↗
PubMed1991

[The relation of the times of onset of vomiting to the magnitude and power of the dose of ionizing radiation].

The paper is concerned with analysis of correlation of the time of appearance of vomit in a person and a mean dose rate of prolonged gamma-radiation in the persons affected at the Chernobyl accident. The data were approximated by power function. For irradiation with a constant dose rate (P) such correlation looks like Tp = 2.48p-0.5, where Tp is the time of the beginning of vomit, hours after the beginning of irradiation. A semiempirical model combining different conditions of irradiation was formed. Prognosis of a severity of lesion with relation to the time of vomit was given for different conditions of irradiation.

Accidents↗
PubMed1991

[Experience in treating the victims of the accident at the Chernobyl Atomic Electric Power Station and the immediate disease outcomes].

The paper is concerned with the results of therapy of 115 patients with acute radiation syndrome after the Chernobyl accident. The chief methods of the effective therapy of bone marrow syndrome are antimicrobial drugs and fresh donor platelet mass transfusions. Hemopoietic stem cell transplantation (allogenic bone marrow or embryonic hepatocytes) is indicated and effective in a very limited number of patients in accident irradiation. Severe beta-burns of the skin remain an unsolved problem as a result of their spreading. Organizational principles of therapy of a great number of patients with acute radiation syndrome in a specialized hospital were described.

Accidents↗
PubMed1990

[An assessment of the contribution of internal irradiation to the early manifestations of acute radiation sickness in the victims of the accident at the Chernobyl Atomic Electric Power Station].

Materials of the investigation of victims of the accident at the Chernobyl Nuclear Power Plant were used for the estimation of a contribution of exposure with incorporated radionuclides to a course of acute radiation syndrome thyroid and pulmonary lesions. Attention was granted to patients who died as a result of accidental exposure. Dose values of thyroid, pulmonary and total body exposure were given. The severity of the affection of the bronchopulmonary and hypophysial-thyroid systems was assessed. The results of cytogenetic investigations to estimate absorbed doses were represented for some persons. Internal exposure was shown to make a considerable effect on the development of acute radiation syndrome in two persons only, internal whole-body exposure doses being compatible with a total exposure dose.

Accidents↗
PubMed1989

[The diagnosis, clinical picture and treatment of acute radiation sickness in the victims of the Chernobyl Atomic Electric Power Station. II. Non-bone marrow syndromes of radiation lesions and their treatment].

Out of 115 victims to the breakdown, 56 persons had radiation burns, 17 the intestinal syndrome, 80 the oropharyngeal syndrome, and 7 interstitial radiation pneumonitis. In the lethal outcome, of crucial importance were radiation burns (over 40% of the body surface) (19 persons) and radiation pneumonitis (7 persons). The grave intestinal and oropharyngeal syndromes were accompanied by other fatal manifestations of radiation injuries. Hemoperfusion, plasmapheresis, continuous heparinization and administration of freshly frozen plasma did not bring about any improvement. The local use of different remedies under aseptic conditions was the leading method of the treatment of radiation burns in the acute period. Parenteral feeding turned out to produce a beneficial effect in the treatment of the intestinal and oropharyngeal syndromes.

Accidents↗