Biomedical subjects
Publications and source records attributed to A K Anand.
Residual iophendylate in the spinal subarachnoid space may closely resemble certain spinal canal tumors on MR imaging of the spine. A knowledge of the appearance on MR imaging scans of iophendylate is essential to differentiate it from spinal tumors.
Fifty-six cases of bronchogenic carcinoma with mediastinal compression were analyzed retrospectively. Microscopic confirmation was obtained in 23 patients and small cell carcinoma was most frequent. Radiation treatment gave complete remission in about 70 per cent when the total tumour dose exceeded 35 Gy fractionated during 3 weeks. Addition of cyclophosphamide marginally increased the remission rate to about 85 per cent. Total tumour doses of less than 35 Gy gave obviously poorer results. The response rate was highest in small cell carcinoma.
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Computed tomography with and without administration of intrathecal contrast material was evaluated in 100 patients with suspected lumbar disk disease. Metrizamide computed tomography was performed in 75 patients and plain computed tomography was performed in 25. Metrizamide computed tomography was more accurate than plain computed tomography. It also disclosed many lesions not shown by metrizamide myelography at the lumbosacral level. Very few lesions were revealed by myelography that were not seen by metrizamide computed tomography. The small amount of intrathecal metrizamide needed for scanning has practically no side effects. Experience in 12 patients indicates that the procedure may be performed safely on an outpatient basis. This study suggests that computed tomography should be given serious consideration as the primary definitive radiographic examination of suspected lumbar disk disease.