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A K Ageev

Publications and source records attributed to A K Ageev.

At least 37 records · Page 2Linked to original sources
PubMed1982

[Clinico-anatomic characteristics of sepsis caused by polymicrobial flora].

Pathological examinations of 23 fatalities due to sepsis caused by polymicrobial flora revealed in 7 cases polymicrobial flora in metastatic foci of dissimilar composition in different foci, in 4 cases monomicrobial flora but varying in different foci, in 12 cases monomicrobial flora similar in all examined septic foci despite the presence in the blood of two or more agents. Localization of metastatic septic foci to a certain extent dependent on the nature of the sepsis causative agents comprising the association. Polymicrobial forms of sepsis were found in fatal cases due to leukemia in 50.0%, to burn sepsis in 10.8%, and to other diseases in 2.8% of the cases, indicating the dependence of their development on the degree of reduction of immunological responsiveness of the patients. The effect of antibacterial therapy given to the patients on the etiology of sepsis is discussed.

Adolescent↗
PubMed1981

[Pathological anatomy and the pathogenetic problems of acute pneumonias of varying etiology].

Acute pneumonias comprise a group of infectious diseases of different etiology which determines many features of clinico-anatomic manifestations of some of their forms including the extension of inflammatory lesions in the lungs. Usually developing due to disorders in the draining function of the bronchi, disorders of the phagocytic activity of leukocytes and alveolar macrophages as well as the presence of immunodeficient conditions, acute pneumonias emerge as complications of other diseases. From 1962 to the present time the rate of their detection in fatal cases increased from 11.6% to 42.8%. Their most frequent causative agents are staphylococci resistant to most antibiotics used for treatment, less frequently Pseudomonas aeruginosa and pathogenic fungi. Also, an increased role in the etiology of pneumonias of conditionally-pathogenic flora (Proteus, Acinetobacter, Enterobacter, Serratia) and frequent pneumonias caused by mixed microflora are observed. Pneumonias were the immediate cause of death in 19.2% of the fatal cases.

Acute Disease↗
PubMed1981

[Patterns in the lesions of different sections of the hemopoietic system in leukemia].

Morphological examinations of the hemopoietic system in 43 patients died of different forms of leukemias revealed irregular involvement into the leukemic processes of its different parts. Differences in the spread of leukemic lesions in the spleen, lymph nodes, tonsils and other lymphoid formations in lympho- and myeloleukemias were demonstrated. They are discussed from the point of view of the concept on metastatic involvement of different parts of the hemopoietic system in leukemias and on the importance in the development of these lesions of the cellular microenvironment. Also, the importance of atrophic changes of the thymus and other lymphoid structures as manifestations of immunological insufficiency which is one of the most significant conditions for the development of leukemia is discussed.

Adult↗
PubMed1979

[Use of a method of staining sections with methyl green-pyronine for histobacterioscopic purposes].

A method of staining of histological sections with methyl green-pyronine for histobacterioscopic detection of microflora in tissues is proposed. A bright red staining with pyronine of microbial agents and yeast-like fungi of the genus Candida due to a high content of RNA in them permits elective detection of their insignificant amounts in tissues even at low magnifications of the microscope.

Bacteriological Techniques↗
PubMed1976

[T- and B-lymphocytes. Distribution in the body, their functional and morphological characteristics and significance].

In a survey of the literature special attention is given to the history of development of concepts concerning the existence in the immunocompetent system of the lymphoid tissue of higher vertebrals and man of two independent to some extent populations of lymphocytes: one dependent on the thymus gland and therefore called T-lymphocytes population, implementing cellular reactions of immunity; and the other, similar one, dependent on Fabricius' bursa in birds and called B-lymphocytes, producing antibodies circulaing in the blood. Functional-morphological characteristics of T-and B-lymphocytes, their distribution in the peripheral organs of the lymphoid system and in the blood are given. The role of T-and B-lymphocytes in rejection of allotransplants and in the reaction of a transplant against the host development of reactions of hypersensitivity of the delayed and immediate types is discussed. The need for a further study of participation of T-and B-lymphocytes in pathogenesis of allergic, autoimmune and numerous other diseases that are accompanied by immune disorders, is emphasized.

Animals↗
PubMed1975

[Pathological anatomy of present-day sepsis].

Analysis of prosector's findings and results of pathoanatomical studies of 65 cases who had died from sepsis showed that its incidence increased from 0.92% in 1956--1960 to 4.11% in 1971-1974. Along with the well-known typical manifestations of sepsis, a number of its perculiar features associated with application of modern therapeutic methods are considered: the prevailing form of sepsis is pyemia (81.5%), considerable incidence of sepsis following peritonitis and septic thrombophlebitis developing at sites of prolonged catheterization of veins. The significance of staphylococci and Bacillus pyocyaneus, which are resistant to the majority of the available at present antibiotics, as principle pathogenes of modern sepsis is emphasized. A dependence between the localization and size of metastatic foci and the kind of pathogene and nature of its toxines is noted. Among the conditions contributing to the development of sepsis the authors consider a reduction of the immunological reactivity of the organism morphologically characterized in the dead persons studied by the absence in lymphatic follicles of lymphatic nodes and the spleen, of "light" centres, drastic atrophic changes in the thymus gland in the majority of cases, and by slightly manifested phenomena of phagocytosis of microbes in the foci of inflammation. The role of operative and other traumas, the character of preceding diseases and application of immunodepressive therapy in the reduction of the immunological reactivity of the organism is tressed.

Adolescent↗